Evidence map›Paper›PMID 38676894›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Swine Model of Myocardial Infarction Induced by Ischemia-Reperfusion and Embolization.

Renata Mazurek, Olympia Bikou, Kiyotake Ishikawa

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Renata MazurekCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Olympia BikouDepartment of Medicine I, LMU University Hospital, LMU Munich, Munich, Germany.
Kiyotake IshikawaCardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. kiyotake.ishikawa@mssm.edu.

Funding

Percutaneous Left Ventricular Unloading for Cardiogenic Shock: Beyond Acute Hemodynamic SupportR01HL139963 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kiyotake Ishikawa · 2018 to 2026
$4.9M
Animal cathlab C-armS10OD034330 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ISHIKAWA, KIYOTAKE · 2023 to 2023
$334k
NHLBI NIH HHS R01 HL139963NIH HHS S10 OD034330
6 · The paper itself

Abstract

Acute myocardial infarction continues to account for a growing burden of heart failure worldwide. Despite existing therapies, new approaches for reducing the extent of damage and better managing heart failure progression are urgently needed. Preclinical large animal models are a critical step in the translation of scientific discoveries toward clinical trials and therapeutic application. In this chapter, we detail methods to induce swine models of myocardial infarction through catheter-mediated approaches involving either temporary (ischemia-reperfusion) or permanent (thrombus injection or embolic coil) occlusions. These techniques are relatively low in invasiveness, while infarct size with corresponding cardiac dysfunction can be controlled by adjusting the location of coronary occlusion. We also describe methods for cardiac angiography and echocardiography in pigs. This is the second edition of a previously published chapter with modifications.

Indexed as

Disease Models, AnimalMyocardial InfarctionMyocardial Reperfusion InjuryAnimalsCoronary AngiographyEchocardiographyEmbolismSwineCoil embolizationCoronary angiographyCoronary microembolizationIschemia-reperfusionMyocardial infarctionNo-reflowPig modelThrombotic MIThrombus injectionTransmural infarction

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.