Evidence map›Paper›PMID 38676881›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Decellularized Extracellular Matrix for Modeling Cardiac Extracellular Microenvironment.

Franca Di Meglio, Daria Nurzynska, Giulia Ricci, Anna Maria Sacco, Clotilde Castaldo

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Franca Di MeglioDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Daria NurzynskaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Baronissi, Italy.
Giulia RicciDepartment of Experimental Medicine, Vanvitelli University, Naples, Italy.
Anna Maria SaccoDepartment of Public Health, University of Naples Federico II, Naples, Italy.
Clotilde CastaldoDepartment of Public Health, University of Naples Federico II, Naples, Italy. clotilde.castaldo@unina.it.
University of Naples Federico II · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extracellular matrix (ECM) forms most of the tissue microenvironment and is in a constant and dynamic equilibrium with cells. The decellularization process employs physical or chemical methods, or a combination of them, to remove the cellular components of tissues and organs while preserving the architecture and composition of the ECM. Depending on the methodology used, the decellularized ECM (dECM) is then suitable for research or clinical applications. Here, we describe an optimized protocol for the efficient decellularization of the human myocardium to generate 3D scaffolds of well-preserved cardiac extracellular matrix that can be used for in vitro or in vivo studies.

Indexed as

Decellularized Extracellular MatrixMyocardiumTissue EngineeringTissue ScaffoldsCellular MicroenvironmentExtracellular MatrixHumansDecellularized Extracellular MatrixAcellular cardiac slicesAcellular myocardial matrixCardiac extracellular matrixCardiac matrix 3D scaffoldsDecellularization

Identifiers

PMID38676881
OpenAlexW4395698853

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.