Evidence map›Paper›PMID 38676841›Full record

ArticleJournal of assisted reproduction and genetics2024

Achilles' heel of male infertility: good LEGO players.

Yang Xuan, Yue Duan

Open access · greenAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yang XuanThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, 310053, China.
Yue DuanDepartment of Urology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, China. dyurology@163.com.ORCID http://orcid.org/0000-0002-4479-4231
Zhejiang Chinese Medical University · CN

Funding

Natural Science Foundation of Zhejiang Province Y20H270024Zhejiang Traditional Chinese Medicine Administration 2022ZZ017
6 · The paper itself

Abstract

In a recent journal article, Chen et al. identified a germ cell-specific cofactor, STYXL1, associated with male fertility function. Deletion of STYXL1 prevents the LEGO player CCT complex from properly folding key microtubule proteins of the sperm flagellum, which affects sperm motility and male fertility function.

Indexed as

Infertility, MaleSperm MotilityHumansMaleMicrotubulesSpermatozoaSperm TailAsthenozoospermiaMale infertilitySTYXL1Tubulin

Identifiers

PMID38676841
PMCPMC11224056
OpenAlexW4395695288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.