Evidence map›Paper›PMID 38676523›Full record

ArticleEndocrine, metabolic & immune disorders drug targets2025

Post-surgical Persistent Hyperparathyroidism Successfully Treated with Parathyroid Radiofrequency Ablation: A Case Report.

Francesco Di Marco, Claudio Cusini, Anna Ferrulli, Giovanni Mauri, Livio Luzi

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Endocrine, metabolic & immune disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Francesco Di MarcoDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID 0009-0000-1573-6828
Claudio CusiniDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS Multi Medica, Sesto San Giovanni (MI), Italy.
Anna FerrulliDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
Giovanni MauriDivision of Interventional Radiology, IEO, European Institute of Oncology IRCCS, 20141, Milan, Italy.
Livio LuziDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
University of Milan · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITMultiMedica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, parathyroidectomy is the standard treatment for Primary Hyperparathyroidism (PHPT). Surgical treatment is often effective, although not free of complications and relapses. Minimally invasive techniques, such as Microwave Ablation (MWA) and Radiofrequency Ablation (RFA), are an alternative to surgery in selected patients. We have, herein, reported on the successful use of RFA in a patient with post-surgical persistent hyperparathyroidism. CASE PRESENTATION: A 54-year-old woman was referred to our Center for mild hypercalcemia with exams revealing Primary Hyperparathyroidism (PHPT). Neck ultrasound and Technetium- 99 Methoxy-isobutyl-isonitrile (99mTc-MIBI) scintigraphy scanning revealed a suspicious right parathyroid hyperplasia/adenoma. She underwent parathyroidectomy and histological examination showed a parathyroid nodular hyperplasia. During the follow-up, she suffered from persistent hyperparathyroidism due to a left parathyroid hyperplasia. Thus she was treated with RFA. Blood tests after the procedure showed the remission of the disease 7 months post-treatment.

conclusionA minimally invasive technique for PHPT may represent a valid alternative to surgery, especially in patients with an elevated surgery-related risk. More studies are necessary to investigate the benefit of RFA as a first-line treatment in PHPT.

Indexed as

Catheter AblationHyperparathyroidismHyperparathyroidism, PrimaryParathyroidectomyParathyroid GlandsPostoperative ComplicationsRadiofrequency AblationFemaleHumansMiddle AgedParathyroid NeoplasmsTreatment Outcomehypercalcemiaminimally invasive techniqueparathyroidectomyparathyroid surgery.persistent hyperparathyroidismPrimary hyperparathyroidismradiofrequency ablation

Identifiers

PMID38676523
OpenAlexW4395695287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.