Evidence map›Paper›PMID 38676463›Full record

Trial reportEarly intervention in psychiatry2024

Race/ethnicity and socioeconomic status as predictors of outcome following family therapy in youth at clinical high risk for psychosis.

Bernalyn Ruiz-Yu, Thanh P Le, Marc J Weintraub, Jamie Zinberg, Jean Addington, Mary P O'Brien, Barbara C Walsh, Michelle Friedman-Yakoobian, Andrea Auther, Cornblatt and 4 more

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Early intervention in psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Bernalyn Ruiz-YuDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.ORCID 0000-0003-3267-6171
Thanh P LeDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.
Marc J WeintraubDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.ORCID 0000-0001-8724-120X
Jamie ZinbergDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.
Jean AddingtonHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-8298-0756
Mary P O'BrienDepartment of Psychology, Yale University, New Haven, Connecticut, USA.
Barbara C WalshDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Michelle Friedman-YakoobianBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Andrea AutherDepartment of Psychiatry Research, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York, USA.
CornblattDepartment of Psychiatry Research, The Zucker Hillside Hospital, Northwell Health, Glen Oaks, New York, USA.
Isabel DominguesDepartment of Psychiatry, University of California, San Diego, California, USA.
Tyrone D CannonDepartment of Psychology, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-5632-3154
David J MiklowitzDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.ORCID 0000-0002-9647-6147
Carrie E BeardenDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.
University of California, Los Angeles · USYale University · USNorthwell Health · USBeth Israel Deaconess Medical Center · USUniversity of Calgary · CAUniversity of California San Diego · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
1/9 Predictors and Mechanisms of Conversion to PsychosisU01MH081902 · NIMH · YALE UNIVERSITY · PI CANNON, TYRONE D · 2008 to 2018
$12.4M
Family-Focused Therapy for Individuals at High Clinical Risk for Psychosis: A Confirmatory Efficacy TrialR01MH123575 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, MIKLOWITZ, DAVID JAY · 2020 to 2023
$5.4M
Clinical Research Training in Schizophrenia and Other PsychosesT32MH122395 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KEITH H NUECHTERLEIN · 2021 to 2026
$1.8M
Prevention Trial of Family Focused Treatment in Youth at Risk for PsychosisRC1MH088546 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CANNON, TYRONE D · 2009 to 2010
$970k
Attias Family FoundationBaszucki Brain Research FundCarl and Roberta Deutsch FoundationNCATS NIH HHS UL1 TR001863NIMH NIH HHS 1RC1MH088546NIMH NIH HHS R01 MH123575NIMH NIH HHS R01MH123575NIMH NIH HHS RC1 MH088546NIMH NIH HHS T32 MH122395NIMH NIH HHS T32MH122395NIMH NIH HHS U01 MH081902NIMH NIH HHS U01MH081902The Max Gray Fund
6 · The paper itself

Abstract

aimThere is limited research on the effects of sociodemographic and socioeconomic factors on treatment outcomes in youth at clinical high risk for psychosis (CHRp). This study examined sociodemographic factors that may affect functional outcomes within this population. Specifically, we investigated the influence of race/ethnicity (dichotomized as non-Hispanic whites [NHW] vs. people of colour [POC]), socioeconomic status (SES; operationalized as parental years of education), and their interaction on change in psychosocial functioning and symptoms over 6 months in a randomized trial of family-focused therapy.

methodsCHRp youth (N = 128) participated in a randomized trial of family therapy (18 sessions of family therapy vs. 3 sessions of family psychoeducation). Sixty-four participants who self-identified as POC and 64 self-identified NHW participants completed baseline and 6-month follow-up measures of positive and negative symptoms and psychosocial (global, role, and social) functioning. Multiple regression models were conducted to test the main effect of race/ethnicity on changes in positive and negative symptoms and functioning, and whether this effect was moderated by parental education.

resultsThere was a significant interaction between race/ethnicity and parental education, such that higher parental education was associated with greater improvement in global functioning in NHW participants, but there was no relationship between parental education and global functioning in POC. Additionally, higher parental education was associated with a decrease in negative symptoms in NHW participants but not in POC. There were no significant effects of race/ethnicity or parental education on positive symptoms, nor on social or role functioning.

conclusionsClinicians may consider tailoring psychosocial treatments according to the needs of diverse families who vary in sociodemographic factors such as educational attainment and race/ethnicity.

Indexed as

Family TherapyPsychotic DisordersSocial ClassAdolescentFemaleHumansMaleTreatment OutcomeYoung Adultclinical high riskfamily therapyparental educationpsychosisrace/ethnicity

Identifiers

PMID38676463
PMCPMC11512687
OpenAlexW4395695296

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.