Evidence map›Paper›PMID 38675965›Full record

ArticleViruses2024

The Effects of Endosomal Toll-like Receptor Inhibitors in an EBV DNA-Exacerbated Inflammatory Bowel Disease Mouse Model.

Iman Karout, Zahraa Salhab, Nour Sherri, Elio R Bitar, Abdul Hamid Borghol, Hady Sabra, Aya Kassem, Omar Osman, Charbel Alam, Sabah Znait and 5 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Iman KaroutDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Zahraa SalhabDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Nour SherriDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Elio R BitarDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.ORCID 0000-0002-0027-8446
Abdul Hamid BorgholDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Hady SabraDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Aya KassemDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Omar OsmanDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.ORCID 0009-0004-7446-1173
Charbel AlamDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Sabah ZnaitDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Rayan AssafDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Sukayna FadlallahDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.
Abdo JurjusDepartment of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Beirut 1107-2020, Lebanon.
Jana G HashashDivision of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL 32224, USA.
Elias A RahalDepartment of Experimental Pathology, Immunology, and Microbiology, American University of Beirut, Beirut 1107-2020, Lebanon.ORCID 0000-0002-1096-7042
American University of Beirut · LBWinnMed · US

Funding

American University of Beirut, Faculty of Medicine Medical Practice Plan
6 · The paper itself

Abstract

Epstein-Barr virus (EBV), a

Indexed as

DNA, ViralHerpesvirus 4, HumanInflammatory Bowel DiseasesToll-Like ReceptorsAnimalsColitisDextran SulfateDisease Models, AnimalEndosomesEpstein-Barr Virus InfectionsFemaleInterleukin-17Membrane GlycoproteinsMiceMice, Inbred C57BLToll-Like Receptor 3Dextran SulfateDNA, ViralInterleukin-17Membrane GlycoproteinsTLR3 protein, mouseTlr7 protein, mouseTlr9 protein, mouseToll-Like Receptor 3Toll-Like Receptor 7Toll-Like Receptor 9Toll-Like Receptorsautoimmune diseasesEpstein–Barr virus (EBV)IL-17Ainflammatory bowel disease (IBD)Toll-like receptors (TLR)

Identifiers

PMID38675965
PMCPMC11054613
OpenAlexW4394879480

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.