Evidence map›Paper›PMID 38675935›Full record

ArticleViruses2024

Molecular and Entomological Characterization of 2023 Dengue Outbreak in Dhading District, Central Nepal.

Sandesh Rimal, Sabin Shrestha, Sunita Wagle Paudel, Yogendra Shah, Govinda Bhandari, Kishor Pandey, Anjana Kharbuja, Merveille Kapandji, Ishan Gautam, Rajshree Bhujel and 11 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Detection of Dengue and Chikungunya Viruses in Mosquitoes from Nepal.The American journal of tropical medicine and hygiene · 2025
    Article
  5. Article
  6. Article
  7. Observational
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 6 institutions in 4 countries.

Sandesh RimalCentral Department of Microbiology, Tribhuvan University, Kathmandu 44601, Nepal.ORCID 0000-0002-8064-3625
Sabin ShresthaCentral Department of Microbiology, Tribhuvan University, Kathmandu 44601, Nepal.ORCID 0000-0002-9522-8547
Sunita Wagle PaudelDhading Hospital, Dhading Besi 45100, Nepal.
Yogendra ShahSeti Provincial Hospital, Dhangadhi 10900, Nepal.ORCID 0000-0002-0820-4556
Govinda BhandariDhading Hospital, Dhading Besi 45100, Nepal.
Kishor PandeyCentral Department of Zoology, Tribhuvan University, Kathmandu 44601, Nepal.
Anjana KharbujaCentral Department of Microbiology, Tribhuvan University, Kathmandu 44601, Nepal.
Merveille KapandjiDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Ishan GautamNatural History Museum, Tribhuvan University, Swayambhu, Kathmandu 44620, Nepal.
Rajshree BhujelCentral Department of Microbiology, Tribhuvan University, Kathmandu 44601, Nepal.
Yuki TakamatsuDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Rudramani BhandariDhading Hospital, Dhading Besi 45100, Nepal.
Chonticha KlungthongArmed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand.
Sanjaya Kumar ShresthaWalter-Reed AFRIMS Research Unit Nepal, Kathmandu 44600, Nepal.
Stefan FernandezArmed Forces Research Institute of Medical Sciences, Bangkok 10400, Thailand.
Gathsaurie Neelika MalavigeFaculty of Medical Sciences, University of Sri Jayewardenepura, Colombo 10250, Sri Lanka.
Basu Dev PandeyDEJIMA Infectious Disease Research Alliance, Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0001-7992-7586
Takeshi UranoDEJIMA Infectious Disease Research Alliance, Nagasaki University, Nagasaki 852-8523, Japan.
Kouichi MoritaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.
Mya Myat Ngwe TunDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki 852-8523, Japan.ORCID 0000-0002-8986-6307
Shyam Prakash DumreCentral Department of Microbiology, Tribhuvan University, Kathmandu 44601, Nepal.ORCID 0000-0002-4072-0745
Tribhuvan University · NPNagasaki University · JPDhulikhel Hospital · NPArmed Forces Research Institute of Medical Science · THShimane University · JPUniversity of Sri Jayewardenepura · LK

Funding

Japan Agency of Medical Research and Development (AMED) JP223fa627004, JP23fk0108656
6 · The paper itself

Abstract

In 2023, Nepal faced its second largest dengue outbreak ever, following a record-breaking number of dengue cases in 2022, characterized by the expansion of infections into areas of higher altitudes. However, the characteristics of the 2023 circulating dengue virus (DENV) and the vector density remain poorly understood. Therefore, we performed DENV serotyping, clinical and laboratory assessment, and entomological analysis of the 2023 outbreak in central Nepal. A total of 396 fever cases in Dhading hospital suspected of being DENV positive were enrolled, and blood samples were collected and tested by different techniques including PCR. Of these, 278 (70.2%) had confirmed DENV infection. Multiple serotypes (DENV-1, -2, and -3) were detected. DENV-2 (97.5%) re-emerged after six years in Dhading while DENV-3 was identified for the first time. Dengue inpatients had significantly higher frequency of anorexia, myalgia, rash, diarrhea, nausea, vomiting, abdominal pain, and thrombocytopenia (

Indexed as

AedesDengueDengue VirusDisease OutbreaksMosquito VectorsSerogroupAdolescentAdultAnimalsChildChild, PreschoolFemaleHumansMaleMiddle AgedNepalAedes spp.dengue outbreak 2023dengue virus serotypesentomological investigationNepalvector density

Identifiers

PMID38675935
PMCPMC11053854
OpenAlexW4394763685

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.