Evidence map›Paper›PMID 38675883›Full record

ArticleViruses2024

Molecular Epidemiology and Clinical Characteristics of an Outbreak on Respiratory Virus Coinfection in Gansu, China.

Wu Liu, Hui Zhang, Tianshuo Zhao, Xianming Cai, Liguo Yang, Genxia Gao, Xiaoyan Che, Zhenhong Zhu, Tongxia Zeng, Fuqiang Cui

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wu LiuJingyuan County Center for Disease Control and Prevention, Jingyuan 730699, China.
Hui ZhangGansu Provincial Center for Disease Control and Prevention, Key Laboratory of Pathogenic Microbiology and Immunology (Gansu Province), Lanzhou 730050, China.
Tianshuo ZhaoDepartment of Health Inspection, Vaccine Research and Evaluation Center, School of Public Health, Peking University, Beijing 101100, China.
Xianming CaiDepartment of Health Inspection, Vaccine Research and Evaluation Center, School of Public Health, Peking University, Beijing 101100, China.
Liguo YangJingyuan County Center for Disease Control and Prevention, Jingyuan 730699, China.
Genxia GaoJingyuan County Center for Disease Control and Prevention, Jingyuan 730699, China.
Xiaoyan CheJingyuan County Center for Disease Control and Prevention, Jingyuan 730699, China.
Zhenhong ZhuJingyuan County Center for Disease Control and Prevention, Jingyuan 730699, China.
Tongxia ZengScientific Research Training Department, Baiyin City Center for Disease Control and Prevention, Baiyin 730900, China.
Fuqiang CuiDepartment of Health Inspection, Vaccine Research and Evaluation Center, School of Public Health, Peking University, Beijing 101100, China.

Funding

Baiyin Science and Technology Project 2022-2-46YNational science and technology Major Project of China 2017ZX10103006Natural Science Foundation of Gansu Province 20JR5RA142
6 · The paper itself

Abstract

This study aims to analyze the epidemiological and pathogenic characteristics of an outbreak primarily caused by respiratory syncytial virus (RSV), human rhinovirus (HRV), and human metapneumovirus (HMPV) in a kindergarten and primary school. The outbreak was investigated by field epidemiological investigation, and the common respiratory pathogens were screened by RT-PCR detection technology. The attack rate of this outbreak was 63.95% (110/172). Main symptoms included cough (85.45%), sore throat (60.91%), and sneezing (60.00%). Multifactorial logistic regression analysis revealed that continuous handwashing and mouth and nose covering when sneezing were protective factors. All 15 collected throat swab specimens tested positive for viruses, with HMPV as the predominant pathogen (80.00%), followed by HRV (53.33%), and two cases of positive respiratory syncytial virus (13.33%). Among them, six samples showed coinfections of HMPV and HRV, and one had coinfections of HMPV and RSV, resulting in a coinfection rate of 46.67%. Genetic sequencing indicated that the HMPV genotype in this outbreak was A2c, and the HRV genotype was type A, resulting in a coinfection outbreak of HMPV, HRV, and RSV in schools and kindergartens, suggesting that multi-pathogen surveillance of respiratory tract infections should be strengthened.

Indexed as

CoinfectionDisease OutbreaksMetapneumovirusMolecular EpidemiologyRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsChildChild, PreschoolChinaFemaleGenotypeHumansMaleParamyxoviridae InfectionsPhylogenyRespiratory Syncytial Virus, Humancoinfectionhuman metapneumovirushuman rhinovirusoutbreakrespiratory syncytial virus

Identifiers

PMID38675883
PMCPMC11054386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.