Evidence map›Paper›PMID 38675768›Full record

ArticleVaccines2024

Lack of Specific Immune Response after Five Doses of mRNA SARS-CoV-2 Vaccine in a Patient with CD4

Trinidad Alba-Cano, Eduardo Fernández-Cruz, Roberto Alonso, Sara Muñoz-Gómez, Rebeca Pérez de Diego, Elena García Martínez, Paloma Sánchez-Mateos, Joaquín Navarro Caspistegui, Mónica Martín López, Juana Gil-Herrera

Open access · goldAbstract readCase Reports
In one paragraph

Article in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Trinidad Alba-CanoDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Eduardo Fernández-CruzDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Roberto AlonsoInstituto de Investigación Sanitaria Gregorio Marañón (IiSGM), 28007 Madrid, Spain.ORCID 0000-0002-0516-6371
Sara Muñoz-GómezDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Rebeca Pérez de DiegoLaboratory of Immunogenetics of Human Diseases, Innate Immunity Group, IdiPAZ Institute for Health Research, La Paz Hospital, 28046 Madrid, Spain.ORCID 0000-0001-8426-8765
Elena García MartínezDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Paloma Sánchez-MateosDepartment of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense, 28040 Madrid, Spain.
Joaquín Navarro CaspisteguiDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Mónica Martín LópezDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Juana Gil-HerreraDivision of Immunology, Hospital General Universitario "Gregorio Marañón", 28007 Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ESUniversidad Complutense de Madrid · ESHospital La Paz Institute for Health Research · ES

Funding

NIH HHS INSIGHT TICO 014
6 · The paper itself

Abstract

Immunogenicity of SARS-CoV-2 mRNA vaccines is highly heterogeneous in patients with inborn errors of immunity (IEIs). This case report analyzes the immune response to mRNA COVID-19 two-dose primary vaccination followed by three boosters in an IEI patient with marked CD4

Indexed as

CD4+ cytopeniaCMVCOVID-19IEIsIgG responseimmunogenicityinborn errors of immunitySARS-CoV-2T-cell responsevaccination

Identifiers

PMID38675768
PMCPMC11054516
OpenAlexW4394567726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.