Evidence map›Paper›PMID 38675758›Full record

ReviewVaccines2024

Live-Attenuated Vaccines in Pediatric Solid Organ Transplant.

Christopher Hartley, Tina Thomas, Sara Kathryn Smith, Wikrom Karnsakul

Open access · goldAbstract readReview
In one paragraph

Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christopher HartleyThe Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.ORCID 0000-0001-8159-387X
Tina ThomasPediatric Liver Center, The Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Sara Kathryn SmithPediatric Liver Center, The Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Wikrom KarnsakulPediatric Liver Center, The Department of Pediatrics, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.ORCID 0000-0001-7288-5459
Johns Hopkins Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measles, mumps, rubella (MMR), and varicella incidence rates have increased due to the delayed vaccination schedules of children secondary to the COVID-19 pandemic. Decreased herd immunity creates a risk for immunocompetent children and immunocompromised individuals in the community. Historically, live-attenuated vaccines (MMR and varicella) were recommended before solid organ transplants. The amount of time before transplant when this is appropriate is often debated, as is the utility of vaccine titers. MMR and varicella vaccines previously were not recommended in immunocompromised patients post-solid organ transplant due to the undue risk of transmission and posed infection risk. The new literature on live-attenuated vaccines in post-transplant pediatric patients provides more insight into the vaccines' safety and efficacy. The present article aims to provide guidance on live-attenuated vaccines (MMR and varicella) in the pre-transplant and post-operative solid organ transplant phases of care in pediatric patients.

Indexed as

live-attenuated vaccinesmeaslesmumpspediatric solid organ transplantprophylaxisrubellavaricella

Identifiers

PMID38675758
PMCPMC11053538
OpenAlexW4393387761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.