Evidence map›Paper›PMID 38675716›Full record

ArticleMolecules (Basel, Switzerland)2024

Beneficial Effects of Dietary Fiber in Young Barley Leaf on Gut Microbiota and Immunity in Mice.

Seita Chudan, Takuto Kurakawa, Miyu Nishikawa, Yoshinori Nagai, Yoshiaki Tabuchi, Shinichi Ikushiro, Yukihiro Furusawa

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Seita ChudanDepartment of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Toyama 939-0398, Japan.
Takuto KurakawaDepartment of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Toyama 939-0398, Japan.
Miyu NishikawaDepartment of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Toyama 939-0398, Japan.
Yoshinori NagaiDepartment of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Toyama 939-0398, Japan.ORCID 0000-0002-5754-5357
Yoshiaki TabuchiDivision of Molecular Genetics Research, Life Science Research Center, University of Toyama, Toyama 930-0194, Japan.ORCID 0000-0002-6007-6176
Shinichi IkushiroDepartment of Biotechnology, Faculty of Engineering, Toyama Prefectural University, Toyama 939-0398, Japan.ORCID 0000-0001-5311-4069
Yukihiro FurusawaDepartment of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University, Toyama 939-0398, Japan.ORCID 0000-0001-6020-6965
Toyama Prefectural University · JPUniversity of Toyama · JP

Funding

Japan Society for the Promotion of Science 20K05929Takeda Science Foundation n/a
6 · The paper itself

Abstract

The health benefits of young barley leaves, rich in dietary fiber, have been studied for several decades; however, their beneficial effects on the intestinal microenvironment remain to be elucidated. To investigate the effects of young barley leaf-derived dietary fiber (YB) on the gut microbiota and immunity, mice were fed an AIN-93G diet containing cellulose or YB and subjected to subsequent analysis. The population of MHC-II-positive conventional dendritic cells (cDCs) and CD86 expression in the cDCs of Peyer's patches were elevated in the YB-fed mice. MHC-II and CD86 expression was also elevated in the bone marrow-derived DCs treated with YB. 16S-based metagenomic analysis revealed that the gut microbiota composition was markedly altered by YB feeding. Among the gut microbiota, Lachnospiraceae, mainly comprising butyrate-producing

Indexed as

Dietary FiberGastrointestinal MicrobiomeHordeumPlant LeavesAnimalsButyratesFecesMiceRetinal DehydrogenaseButyratesDietary FiberRetinal DehydrogenaseDectin-1dendritic celldietary fibergut bacteriaIgAretinoic acidshort-chain fatty acidyoung barley leaf

Identifiers

PMID38675716
PMCPMC11054971
OpenAlexW4395011028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.