Evidence map›Paper›PMID 38675558›Full record

ArticleMolecules (Basel, Switzerland)2024

A Novel Non-Psychoactive Fatty Acid from a Marine Snail,

Christina Sathyanathan Vijayaraghavan, Lakshmi Sundaram Raman, Shanmugapriya Surenderan, Harpreet Kaur, Mohanapriya Dandapani Chinambedu, Sadras Panchatcharam Thyagarajan, Mary Elizabeth Gnanambal Krishnan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christina Sathyanathan VijayaraghavanDepartment of Biotechnology, Faculty of Biomedical Sciences and Technology, SRI Ramachandra Institute of Higher Education and Research (SRIHER), Deemed to be University (DU), Porur, Chennai 600116, Tamil Nadu, India.
Lakshmi Sundaram RamanFaculty of Pharmacy, SRI RAMACHANDRA Institute of Higher Education and Research (SRIHER), Deemed to be University (DU), Porur, Chennai 600116, Tamil Nadu, India.
Shanmugapriya SurenderanWhizbang Bioresearch Private Limited, Porur, Chennai 600077, Tamil Nadu, India.
Harpreet KaurDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, SRI Ramachandra Institute of Higher Education and Research (SRIHER), Deemed to be University (DU), Porur, Chennai 600116, Tamil Nadu, India.ORCID 0000-0002-9535-5781
Mohanapriya Dandapani ChinambeduDepartment of Human Genetics, Faculty of Biomedical Sciences and Technology, SRI Ramachandra Institute of Higher Education and Research (SRIHER), Deemed to be University (DU), Porur, Chennai 600116, Tamil Nadu, India.
Sadras Panchatcharam ThyagarajanDistinguished Professor and Advisor to Chancellor, Vellore Institute of technology (VIT), Vellore Campus, Tiruvalam Rd, Katpadi, Vellore 632014, Tamil Nadu, India.
Mary Elizabeth Gnanambal KrishnanDepartment of Biotechnology, Faculty of Biomedical Sciences and Technology, SRI Ramachandra Institute of Higher Education and Research (SRIHER), Deemed to be University (DU), Porur, Chennai 600116, Tamil Nadu, India.ORCID 0000-0001-9323-7434
Sri Ramachandra Institute of Higher Education and Research · INVellore Institute of Technology University · IN

Funding

Science and Engineering Research Board (SERB) SR/SO/BB-0005/2009
6 · The paper itself

Abstract

The cannabinoid-type I (CB1) receptor functions as a double-edged sword to decide cell fate: apoptosis/survival. Elevated CB1 receptor expression is shown to cause acute ceramide accumulation to meet the energy requirements of fast-growing cancers. However, the flip side of continual CB1 activation is the initiation of a second ceramide peak that leads to cell death. In this study, we used ovarian cancer cells, PA1, which expressed CB1, which increased threefold when treated with a natural compound, bis(palmitoleic acid) ester of a glycerol (

Indexed as

ApoptosisCeramidesConus SnailFatty AcidsReceptor, Cannabinoid, CB1AnimalsCell Line, TumorFemaleHumansSignal TransductionCeramidesFatty AcidsReceptor, Cannabinoid, CB1apoptosiscannabinoid receptor 1 (CB1)ceramideFAAH1MD simulationovarian cancerzebrafish models

Identifiers

PMID38675558
PMCPMC11052367
OpenAlexW4394755677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.