Evidence map›Paper›PMID 38675489›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Comparison of Glioblastoma Cell Culture Platforms Based on Transcriptional Similarity with Paired Tissue.

Junseong Park, Ilkyoo Koh, Junghwa Cha, Yoojung Oh, Jin-Kyoung Shim, Hyejin Kim, Ju Hyung Moon, Eui Hyun Kim, Jong Hee Chang, Pilnam Kim and 1 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Junseong ParkDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0003-0436-8614
Ilkyoo KohDepartment of Bio and Brain Engineering, KAIST, Daejeon 34141, Republic of Korea.
Junghwa ChaDepartment of Bio and Brain Engineering, KAIST, Daejeon 34141, Republic of Korea.
Yoojung OhDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-5409-9868
Jin-Kyoung ShimDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Hyejin KimDepartment of Bio and Brain Engineering, KAIST, Daejeon 34141, Republic of Korea.
Ju Hyung MoonDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-8925-5821
Eui Hyun KimDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0002-2523-7122
Jong Hee ChangDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Pilnam KimDepartment of Bio and Brain Engineering, KAIST, Daejeon 34141, Republic of Korea.
Seok-Gu KangDepartment of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.ORCID 0000-0001-5676-2037

Funding

Korea Health Industry Development Institute HI14C1324National Research Foundation of Korea NRF-2020M2D9A2092372National Research Foundation of Korea NRF-2021R1I1A1A01048717National Research Foundation of Korea NRF-2022M3C1A309202211National Research Foundation of Korea NRF-2022R1A2B5B03001199Yonsei University 6-2022-0147
6 · The paper itself

Abstract

No standardized in vitro cell culture models for glioblastoma (GBM) have yet been established, excluding the traditional two-dimensional culture. GBM tumorspheres (TSs) have been highlighted as a good model platform for testing drug effects and characterizing specific features of GBM, but a detailed evaluation of their suitability and comparative performance is lacking. Here, we isolated GBM TSs and extracellular matrices (ECM) from tissues obtained from newly diagnosed

Indexed as

cell culture platformextracellular matrixglioblastomapatient-derived tumorspheretranscriptional program

Identifiers

PMID38675489
PMCPMC11054899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.