Evidence map›Paper›PMID 38675393›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Discovery of Bacterial Key Genes from 16S rRNA-Seq Profiles That Are Associated with the Complications of SARS-CoV-2 Infections and Provide Therapeutic Indications.

Md Kaderi Kibria, Md Ahad Ali, Muhammad Yaseen, Imran Ahmad Khan, Mashooq Ahmad Bhat, Md Ariful Islam, Rashidul Alam Mahumud, Md Nurul Haque Mollah

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Md Kaderi KibriaBioinformatics Laboratory, Department of Statistics, University of Rajshahi, Rajshahi 6205, Bangladesh.
Md Ahad AliBioinformatics Laboratory, Department of Statistics, University of Rajshahi, Rajshahi 6205, Bangladesh.ORCID 0000-0002-9200-7669
Muhammad YaseenInstitute of Chemical Sciences, University of Swat, Main Campus, Charbagh 19130, Pakistan.ORCID 0000-0002-2259-4589
Imran Ahmad KhanDepartment of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Mashooq Ahmad BhatDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11421, Saudi Arabia.ORCID 0000-0001-8426-4692
Md Ariful IslamBioinformatics Laboratory, Department of Statistics, University of Rajshahi, Rajshahi 6205, Bangladesh.ORCID 0000-0003-2789-000X
Rashidul Alam MahumudNHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia.
Md Nurul Haque MollahBioinformatics Laboratory, Department of Statistics, University of Rajshahi, Rajshahi 6205, Bangladesh.ORCID 0000-0002-3883-3396
University of Rajshahi · BDGovernment College University, Faisalabad · PKHajee Mohammad Danesh Science and Technology University · BDKing Saud University · SAThe University of Sydney · AUUniversity of Swat · PK

Funding

BANBEIS Research Project, Govt. of Bangladesh MS20191106, 2019-2022King Saud University, Riyadh, Saudi Arabia RSPD2024R740
6 · The paper itself

Abstract

SARS-CoV-2 infections, commonly referred to as COVID-19, remain a critical risk to both human life and global economies. Particularly, COVID-19 patients with weak immunity may suffer from different complications due to the bacterial co-infections/super-infections/secondary infections. Therefore, different variants of alternative antibacterial therapeutic agents are required to inhibit those infection-causing drug-resistant pathogenic bacteria. This study attempted to explore these bacterial pathogens and their inhibitors by using integrated statistical and bioinformatics approaches. By analyzing bacterial 16S rRNA sequence profiles, at first, we detected five bacterial genera and taxa (

Indexed as

16S rRNA-seq profilesbacterial co-infectionsbacterial key genes (bKGs)bioinformatics analysisdrug repurposingSARS-CoV-2 infections

Identifiers

PMID38675393
PMCPMC11053588
OpenAlexW4393278619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.