Evidence map›Paper›PMID 38675390›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Significance of Cytomegalovirus gB Genotypes in Adult Patients Undergoing Hematopoietic Stem Cell Transplantation: Insights from a Single-Centre Investigation.

Tamara Vasiljevic, Marko Jankovic, Ana Tomic, Ida Bakrac, Stefan Radenovic, Danijela Miljanovic, Aleksandra Knezevic, Tanja Jovanovic, Irena Djunic, Milena Todorovic-Balint

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tamara VasiljevicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.
Marko JankovicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.ORCID 0000-0001-5993-0577
Ana TomicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.ORCID 0009-0003-4212-0182
Ida BakracFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.
Stefan RadenovicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.
Danijela MiljanovicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.ORCID 0000-0001-9446-8701
Aleksandra KnezevicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.ORCID 0000-0003-3451-810X
Tanja JovanovicInstitute for Biocides and Medical Ecology, 16 Trebevicka Street, 11000 Belgrade, Serbia.ORCID 0009-0002-0636-2048
Irena DjunicFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.
Milena Todorovic-BalintFaculty of Medicine, University of Belgrade, 8 Dr Subotica Street, 11000 Belgrade, Serbia.ORCID 0000-0002-0958-8811
University of Belgrade · RS

Funding

Wellcome Trust 200110
6 · The paper itself

Abstract

introductionCytomegalovirus (CMV) infection is a major clinical issue after allogeneic hematopoietic stem cell transplantation (HSCT). The CMV envelope glycoproteins are key in viral pathogenesis; the glycoprotein B (gB) encoded by the

resultsThe most prevalent genotypes were gB1 and gB4 (11/27, 40.7%). Patients with genotype gB1 infection had earlier platelet engraftment ( MATERIAL AND

methodsThe study included fifty-nine adult patients treated with allogeneic HSCT. Peripheral venous blood was sampled typically per week, with detection of CMV performed by quantitative real-time PCR. Multiplex nested PCR was used to determine specific gB genotypes, which were then statistically compared vis-à-vis specific clinical variables.

conclusionsOur study points to variations in the viral

Indexed as

adultcytomegalovirusgB genotypeGvHDhematopoietic stem cell transplant

Identifiers

PMID38675390
PMCPMC11054653
OpenAlexW4393218075

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.