Evidence map›Paper›PMID 38675368›Full record

ArticlePharmaceuticals (Basel, Switzerland)2024

Current Perspectives on Biological Screening of Newly Synthetised Sulfanilamide Schiff Bases as Promising Antibacterial and Antibiofilm Agents.

Maria Coanda, Carmen Limban, Constantin Draghici, Anne-Marie Ciobanu, Georgiana Alexandra Grigore, Marcela Popa, Miruna Stan, Cristina Larion, Speranta Avram, Catalina Mares and 6 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Antibiotics (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Maria CoandaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania.
Carmen LimbanDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania.
Constantin DraghiciCostin D. Nenitzescu Institute of Organic and Supramolecular Chemistry, 202 B Splaiul Independentei, 060023 Bucharest, Romania.
Anne-Marie CiobanuDepartment of Drug Control, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania.ORCID 0000-0002-1132-9093
Georgiana Alexandra GrigoreFaculty of Biology, University of Bucharest, Splaiul Independenței 91-95, 050095 Bucharest, Romania.
Marcela PopaFaculty of Biology, University of Bucharest, Splaiul Independenței 91-95, 050095 Bucharest, Romania.
Miruna StanFaculty of Biology, University of Bucharest, Splaiul Independenței 91-95, 050095 Bucharest, Romania.ORCID 0000-0002-6273-8540
Cristina LarionResearch Institute of the University of Bucharest (ICUB), University of Bucharest, Șoseaua Panduri 90, 050663 Bucharest, Romania.
Speranta AvramDepartment of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Splaiul Independentei 91-95, 050095 Bucharest, Romania.
Catalina MaresDepartment of Anatomy, Animal Physiology and Biophysics, Faculty of Biology, University of Bucharest, Splaiul Independentei 91-95, 050095 Bucharest, Romania.ORCID 0000-0002-7825-1323
Mariana-Catalina CiorneiPhysiology Department, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Aura DabuNeurosurgery Department 1, The University Emergency Hospital of Bucharest, Splaiul Independenței 169, 050098 Bucharest, Romania.
Ariana HuditaFaculty of Biology, University of Bucharest, Splaiul Independenței 91-95, 050095 Bucharest, Romania.ORCID 0000-0002-9439-9432
Bianca GalateanuFaculty of Biology, University of Bucharest, Splaiul Independenței 91-95, 050095 Bucharest, Romania.
Lucia PintilieNational Institute for Chemical-Pharmaceutical Research and Development, 112 Vitan Av., 031299 Bucharest, Romania.ORCID 0000-0002-1036-7653
Diana Camelia NutaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Str., 020950 Bucharest, Romania.ORCID 0000-0002-7685-3291
University of Bucharest · ROCarol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RONational Institute For Chemical Pharmaceutical Research and Development · RO

Funding

Ministerul Cercetării și Inovării 104TE/2022 - PN-III-P1-1.1-TE-2021-1660
6 · The paper itself

Abstract

Growing resistance to antimicrobials, combined with pathogens that form biofilms, presents significant challenges in healthcare. Modifying current antimicrobial agents is an economical approach to developing novel molecules that could exhibit biological activity. Thus, five sulfanilamide Schiff bases were synthesized under microwave irradiation and characterized spectroscopically and in silico. They were evaluated for their antimicrobial and antibiofilm activities against both Gram-positive and Gram-negative bacterial strains. Their cytotoxic potential against two cancer cell lines was also determined. Gram-positive bacteria were susceptible to the action of these compounds. Derivatives

Indexed as

antibiofilmantimicrobialcytotoxicitySchiff basesulfanilamide

Identifiers

PMID38675368
PMCPMC11053482
OpenAlexW4393082451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.