Evidence map›Paper›PMID 38675248›Full record

ArticleMicromachines2024

Photothermal-Based Multiplex Nested Digital PCR System for Rapid Detection of Foodborne Pathogens.

Junwei Li, Xinyi Liang, Jinsong Ma, Jianye Cheng, Hui Wang, Xuzhao Wang, Jie Jayne Wu, Hailong An

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Junwei LiInstitute of Biophysics, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300401, China.ORCID 0000-0002-1724-4752
Xinyi LiangSchool of Science, Hebei University of Technology, Tianjin 300401, China.
Jinsong MaSchool of Mechanical Engineering, Hebei University of Technology, Tianjin 300401, China.
Jianye ChengSchool of Mechanical Engineering, Hebei University of Technology, Tianjin 300401, China.
Hui WangInstitute of Biophysics, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300401, China.
Xuzhao WangInstitute of Biophysics, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300401, China.ORCID 0000-0001-6278-0346
Jie Jayne WuDepartment of Electrical Engineering and Computer Science, The University of Tennessee, Knoxville, TN 37996, USA.ORCID 0000-0001-5143-9425
Hailong AnInstitute of Biophysics, School of Health Sciences and Biomedical Engineering, Hebei University of Technology, Tianjin 300401, China.
Hebei University of Technology · CN

Funding

Department of Human Resources and Social Security of Hebei Province C20210337Hebei Province Higher Education Science and Technology Research Project JZX2023013Natural Science Foundation of Hebei Province of China F2023202049, and C2021202001Tianjin Science and Technology Supporting Plan S23ZC86381
6 · The paper itself

Abstract

The rapid and sensitive detection of foodborne pathogens is crucial for ensuring food safety. Among virus testing methods, polymerase chain reaction (PCR) has served as the gold-standard technique in most food safety regulation organizations. However, to enhance the speed and efficiency of PCR, novel approaches are continually being explored. In this work, leveraging the photothermal effects and high thermal conductivity of gold nanoparticles, we have significantly improved the heating and cooling rates of thermal cycles, enabling ultra-fast PCR detection. Specifically, we present a pre-degassing multiplex digital PCR chip integrated with gold nanoparticles. We further developed a portable system with a light source for photothermal heating cycling, along with an optoelectronic sensor to analyze PCR amplification products after rapid thermal cycling. As proof of concept, the proposed chip and portable device was applied for the on-site detection of several types of foodborne pathogens, including Escherichia coli, Listeria monocytogenes, Staphylococcus aureus, and

Indexed as

digital PCRfoodborne pathogensmultiplexphotothermal effect

Identifiers

PMID38675248
PMCPMC11052467
OpenAlexW4393142844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.