Evidence map›Paper›PMID 38675182›Full record

ArticlePharmaceutics2024

Comparative Cytotoxicity of Menthol and Eucalyptol: An In Vitro Study on Human Gingival Fibroblasts.

Clara Puig-Herreros, José Luis Sanz, David García-Bernal, Francisco Javier Rodríguez-Lozano, Laura Murcia, Leopoldo Forner, James Ghilotti, Ricardo E Oñate-Sánchez, Sergio López-García

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Clara Puig-HerrerosSpeech Therapy University Clinic, Department of Basic Psychology, Universitat de València, 46010 Valencia, Spain.ORCID 0000-0001-5697-4953
José Luis SanzDepartament d'Estomatologia, Facultat de Medicina i Odontologia, Universitat de València, 46010 Valencia, Spain.ORCID 0000-0002-5438-8085
David García-BernalDepartment of Biochemistry, Molecular Biology B and Immunology, Faculty of Medicine, University of Murcia, 30120 Murcia, Spain.ORCID 0000-0001-6610-8442
Francisco Javier Rodríguez-LozanoBiomedical Research Institute (IMIB), 30120 Murcia, Spain.ORCID 0000-0002-0623-740X
Laura MurciaDepartment of Health Sciences, Catholic University San Antonio of Murcia, 30107 Murcia, Spain.ORCID 0000-0001-7768-0989
Leopoldo FornerDepartament d'Estomatologia, Facultat de Medicina i Odontologia, Universitat de València, 46010 Valencia, Spain.ORCID 0000-0002-8603-9883
James GhilottiDepartament d'Estomatologia, Facultat de Medicina i Odontologia, Universitat de València, 46010 Valencia, Spain.
Ricardo E Oñate-SánchezDepartment of Dermatology, Stomatology, Radiology and Physical Medicine, Morales Meseguer Hospital, Faculty of Medicine, University of Murcia, 30008 Murcia, Spain.
Sergio López-GarcíaDepartament d'Estomatologia, Facultat de Medicina i Odontologia, Universitat de València, 46010 Valencia, Spain.ORCID 0000-0001-5467-392X
Universitat de València · ESInstituto Murciano de Investigación Biosanitaria · ESUniversidad Católica de Murcia · ESUniversidad de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the influence of eucalyptol and menthol on the cell viability, migration, and reactive oxygen species production of human gingival fibroblasts (GFs) in vitro. Three different concentrations of eucalyptol and menthol were prepared following ISO 10993-5 guidelines (1, 5, and 10 mM). GFs were isolated from extracted teeth from healthy donors. The following parameters were assessed: cell viability via MTT, Annexin-V-FITC and 7-AAD staining, and IC

Indexed as

cytotoxicityeucalyptolgingival fibroblastsmenthol

Identifiers

PMID38675182
PMCPMC11054097
OpenAlexW4394610923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.