Evidence map›Paper›PMID 38675174›Full record

ArticlePharmaceutics2024

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics.

Karim Obeid, Panagiotis Kanellopoulos, Ayman Abouzayed, Adam Mattsson, Vladimir Tolmachev, Berthold A Nock, Theodosia Maina, Anna Orlova

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. RM2 and DB15 analogues bearing [EJNMMI radiopharmacy and chemistry · 2025
    Article
  5. NovelPharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Reshaping [Pharmaceutics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Karim ObeidDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Panagiotis KanellopoulosDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0002-0617-3936
Ayman AbouzayedDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Adam MattssonDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.
Vladimir TolmachevDepartment of Immunology, Genetics and Pathology, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0002-6122-1734
Berthold A NockMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-6028-9112
Theodosia MainaMolecular Radiopharmacy, INRaSTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-1123-2486
Anna OrlovaDepartment of Medicinal Chemistry, Uppsala University, 751 83 Uppsala, Sweden.ORCID 0000-0001-6120-2683
Uppsala University · SENational Centre of Scientific Research "Demokritos" · GR

Funding

Swedish Cancer Society 21 1485 PjSwedish Cancer Society 23 2645 PjF 01HSwedish Research Council 2022-00556Swedish Research Council 2023-02158
6 · The paper itself

Abstract

Gastrin-releasing peptide receptor (GRPR)-antagonists have served as motifs in the development of theranostic radioligands for prostate cancer. Our efforts have been focused on the development of radiolabeled RM26 (H-DPhe

Indexed as

GRPRGRPR-antagonistneprilysinPC-3 cell/tumorpositively charged linkerprostate cancerradiotheranostics

Identifiers

PMID38675174
PMCPMC11054746
OpenAlexW4394579609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.