Evidence map›Paper›PMID 38675156›Full record

ArticlePharmaceutics2024

Fine-Tuning the Amphiphilic Properties of Carbosilane Dendritic Networks towards High-Swelling Thermogels.

Silvia Muñoz-Sánchez, Andrea Barrios-Gumiel, Francisco Javier de la Mata, Sandra García-Gallego

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Functional Self-Immolative Hydrogels with Dendritic Cross-Linkers for Controlled Drug Delivery.Chemistry of materials : a publication of the American Chemical Society · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Silvia Muñoz-SánchezUniversity of Alcala, Faculty of Sciences, Department of Organic and Inorganic Chemistry, and Research Institute in Chemistry "Andrés M. Del Río" (IQAR), 28805 Madrid, Spain.
Andrea Barrios-GumielUniversity of Alcala, Faculty of Sciences, Department of Organic and Inorganic Chemistry, and Research Institute in Chemistry "Andrés M. Del Río" (IQAR), 28805 Madrid, Spain.
Francisco Javier de la MataUniversity of Alcala, Faculty of Sciences, Department of Organic and Inorganic Chemistry, and Research Institute in Chemistry "Andrés M. Del Río" (IQAR), 28805 Madrid, Spain.ORCID 0000-0003-0418-3935
Sandra García-GallegoUniversity of Alcala, Faculty of Sciences, Department of Organic and Inorganic Chemistry, and Research Institute in Chemistry "Andrés M. Del Río" (IQAR), 28805 Madrid, Spain.ORCID 0000-0001-6112-0450
Universidad de Alcalá · ES

Funding

Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine CIBER-BBNComunidad de Madrid CM/BG/2021-01Comunidad de Madrid CM/JIN/2021-003Comunidad de Madrid REACT UE-CM2021-01Junta de Comunidades de Castilla-la Mancha SBPLY/19/180501/000269Ministerio de Ciencia e Innovación PID2020112924RB-100Ministerio de Universidades BG20/00231
6 · The paper itself

Abstract

Dendritic hydrogels based on carbosilane crosslinkers are promising drug delivery systems, as their amphiphilic nature improves the compatibility with poorly water-soluble drugs. In this work, we explored the impact of the complementary polymer on the amphiphilic properties of the dendritic network. Different polymers were selected as precursors, from the highly lipophilic propylene glycol (PPG) to the hydrophilic polyethylene glycol (PEG), including amphiphilic Pluronics L31, L35 and L61. The dithiol polymers reacted with carbosilane crosslinkers through UV-initiated thiol-ene coupling (TEC), and the resultant materials were classified as non-swelling networks (for PPG, PLU

Indexed as

dendrimerdendrondrug deliveryhydrogelnetworkpolymerthermogelthermo-responsive

Identifiers

PMID38675156
PMCPMC11054174
OpenAlexW4393871207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.