Evidence map›Paper›PMID 38675152›Full record

ArticlePharmaceutics2024

Use of Plant Extracts in Polymeric Scaffolds in the Regeneration of Mandibular Injuries.

Bruna Eduarda Gandra de Oliveira, Fernanda Latorre Melgaço Maia, Lívia Contini Massimino, Claudio Fernandes Garcia, Ana Maria de Guzzi Plepis, Virgínia da Conceição Amaro Martins, Carlos Henrique Bertoni Reis, Vinícius Rodrigues Silva, Andre Alves Bezerra, Carolina Chen Pauris and 4 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Electrospun Fibers EncapsulatingMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Bruna Eduarda Gandra de OliveiraOrthopedics and Traumatology Sector, Faculty of Medicine of Jundiaí, Jundiaí 13202-550, Brazil.
Fernanda Latorre Melgaço MaiaDepartment of Implant Dentistry, Faculdade São Leopoldo Mandic, Campinas 13045-755, Brazil.
Lívia Contini MassiminoInterunit Postgraduate Program in Bioengineering (EESC/FMRP/IQSC), University of São Paulo (USP), São Carlos 13566-590, Brazil.
Claudio Fernandes GarciaSão Carlos Institute of Chemistry, University of São Paulo, USP, São Carlos 13566-590, Brazil.
Ana Maria de Guzzi PlepisInterunit Postgraduate Program in Bioengineering (EESC/FMRP/IQSC), University of São Paulo (USP), São Carlos 13566-590, Brazil.ORCID 0000-0002-4360-8433
Virgínia da Conceição Amaro MartinsSão Carlos Institute of Chemistry, University of São Paulo, USP, São Carlos 13566-590, Brazil.
Carlos Henrique Bertoni ReisPostgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marilia (UNIMAR), Marília 17525-902, Brazil.
Vinícius Rodrigues SilvaDepartment of Human Anatomy, University of San Francisco (USF), Bragança Paulista 12916-900, Brazil.
Andre Alves BezerraOrthopedics and Traumatology Sector, Faculty of Medicine of Jundiaí, Jundiaí 13202-550, Brazil.
Carolina Chen PaurisPostgraduate Program in Health Sciences, Faculty of Medicine of Jundiaí, Jundiaí 13202-550, Brazil.
Daniela Vieira BuchaimPostgraduate Program in Structural and Functional Interactions in Rehabilitation, University of Marilia (UNIMAR), Marília 17525-902, Brazil.ORCID 0000-0002-9914-1262
Yggor Biloria E SilvaPostgraduate Program in Health Sciences, Faculty of Medicine of Jundiaí, Jundiaí 13202-550, Brazil.
Rogerio Leone BuchaimDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo (FOB/USP), Bauru 17012-901, Brazil.ORCID 0000-0002-5881-2218
Marcelo Rodrigues da CunhaInterunit Postgraduate Program in Bioengineering (EESC/FMRP/IQSC), University of São Paulo (USP), São Carlos 13566-590, Brazil.
Universidade Federal de São Carlos · BRFaculdade de Medicina de Jundiaí · BRUniversidade de São Paulo · BRFaculdade São Leopoldo Mandic · BRUniversidade São Francisco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe loss of bone mass may require grafting, and, among the alternatives available, there are natural biomaterials that can act as scaffolds for the cell growth necessary for tissue regeneration. Collagen and elastin polymers are a good alternative due to their biomimetic properties of bone tissue, and their characteristics can be improved with the addition of polysaccharides such as chitosan and bioactive compounds such as jatoba resin and pomegranate extract due to their antigenic actions. The aim of this experimental protocol was to evaluate bone neoformation in experimentally made defects in the mandible of rats using polymeric scaffolds with plant extracts added. Thirty rats were divided into group 1, with a mandibular defect filled with a clot from the lesion and no graft implant (G1-C,

Indexed as

bone regenerationbone repaircollagenelastinhydroxyapatitejatobaplant extractspolymerspomegranatescaffolds

Identifiers

PMID38675152
PMCPMC11053713
OpenAlexW4393525279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.