Evidence map›Paper›PMID 38675140›Full record

ReviewPharmaceutics2024

Enhancing Precision in Photodynamic Therapy: Innovations in Light-Driven and Bioorthogonal Activation.

Natalia S Kuzmina, Ekaterina A Fedotova, Petar Jankovic, Galina P Gribova, Alexander V Nyuchev, Alexey Yu Fedorov, Vasilii F Otvagin

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Natural Chlorin eACS omega · 2026
    Article
  2. Light as a Weapon: Redefining Cancer Care with Photodynamic Therapy.International journal of biological sciences · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Natalia S KuzminaDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.ORCID 0000-0001-9609-1717
Ekaterina A FedotovaDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.
Petar JankovicDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.
Galina P GribovaDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.
Alexander V NyuchevDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.ORCID 0000-0002-0460-0543
Alexey Yu FedorovDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.
Vasilii F OtvaginDepartment of Organic Chemistry, Lobachevsky State University of Nizhny Novgorod, Gagarina Av. 23, 603950 Nizhny Novgorod, Russia.ORCID 0000-0001-6015-099X
N. I. Lobachevsky State University of Nizhny Novgorod · RU

Funding

Russian Science Foundation 21-73-10230
6 · The paper itself

Abstract

Over the past few decades, photodynamic therapy (PDT) has evolved as a minimally invasive treatment modality offering precise control over cancer and various other diseases. To address inherent challenges associated with PDT, researchers have been exploring two promising avenues: the development of intelligent photosensitizers activated through light-induced energy transfers, charges, or electron transfers, and the disruption of photosensitive bonds. Moreover, there is a growing emphasis on the bioorthogonal delivery or activation of photosensitizers within tumors, enabling targeted deployment and activation of these intelligent photosensitive systems in specific tissues, thus achieving highly precise PDT. This concise review highlights advancements made over the last decade in the realm of light-activated or bioorthogonal photosensitizers, comparing their efficacy and shaping future directions in the advancement of photodynamic therapy.

Indexed as

active targetingbioorthogonal chemistrycombination therapyphotodynamic therapyphotosensitizersselective photodynamic therapysensing mechanisms

Identifiers

PMID38675140
PMCPMC11053670
OpenAlexW4393352971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.