Evidence map›Paper›PMID 38674966›Full record

ArticlePolymers2024

Antimicrobial Efficacy of a Vegetable Oil Plasticizer in PVC Matrices.

Greta Bajetto, Sara Scutera, Francesca Menotti, Giuliana Banche, Giuseppe Chiaradia, Caterina Turesso, Marco De Andrea, Marta Vallino, Daan S Van Es, Matteo Biolatti and 2 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Greta BajettoDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.ORCID 0000-0002-2339-2479
Sara ScuteraDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.ORCID 0000-0002-7431-0875
Francesca MenottiDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.
Giuliana BancheDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.ORCID 0000-0003-2219-0223
Giuseppe ChiaradiaFluos Sas, 21052 Busto Arsizio, Italy.
Caterina TuressoFluos Sas, 21052 Busto Arsizio, Italy.
Marco De AndreaDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.ORCID 0000-0002-3188-5783
Marta VallinoInstitute for Sustainable Plant Protection, National Research Centre (CNR), 10135 Turin, Italy.
Daan S Van EsWageningen Food & Biobased Research, 6708 WG Wageningen, The Netherlands.ORCID 0000-0001-7476-5813
Matteo BiolattiDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.ORCID 0000-0001-7675-0762
Valentina Dell'OsteDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.ORCID 0000-0002-9336-7906
Tiziana MussoDepartment of Public Health and Pediatric Sciences, University of Turin, 10100 Turin, Italy.
University of Turin · ITOspedale di Circolo di Busto Arsizio · ITInstitute for Sustainable Plant Protection · ITWageningen University & Research · NL

Funding

"Cassa di Risparmio" Foundation of Turin RF=2021.1745"Cassa di Risparmio" Foundation of Turin RF=2021.1800Italian Ministry of University and Research-MUR PRIN 2022N7EXJMItalian Ministry of University and Research-MUR PRIN 2022S3AZCCMUR PNRR Extended Partnership initiative on Emerging Infectious Diseases PE00000007University of Turin "Ricerca Locale" 2022/23
6 · The paper itself

Abstract

The growing prevalence of bacterial and viral infections, highlighted by the recent COVID-19 pandemic, urgently calls for new antimicrobial strategies. To this end, we have synthesized and characterized a novel fatty acid epoxy-ester plasticizer for polymers, named GDE. GDE is not only sustainable and user-friendly but also demonstrates superior plasticizing properties, while its epoxy components improve the heat stability of PVC-based matrices. A key feature of GDE is its ability to confer antimicrobial properties to surfaces. Indeed, upon contact, this material can effectively kill enveloped viruses, such as herpes simplex virus type 1 (HSV-1) and the β-coronavirus prototype HCoV-OC43, but it is ineffective against nonenveloped viruses like human adenovirus (HAdV). Further analysis using transmission electron microscopy (TEM) on HSV-1 virions exposed to GDE showed significant structural damage, indicating that GDE can interfere with the viral envelope, potentially causing leakage. Moreover, GDE demonstrates antibacterial activity, albeit to a lesser extent, against notorious pathogens such as

Indexed as

antiviral and antibacterial polymersbiomaterialsmedical devicesplasticizerspolyvinyl chloride (PVC)vegetable oils

Identifiers

PMID38674966
PMCPMC11054656
OpenAlexW4394676167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.