Evidence map›Paper›PMID 38674918›Full record

Trial reportNutrients2024

Effects of Gluten on Gut Microbiota in Patients with Gastrointestinal Disorders, Migraine, and Dermatitis.

Ismael San Mauro Martín, Sara López Oliva, Elena Garicano Vilar, Guerthy Melissa Sánchez Niño, Bruno F Penadés, Ana Terrén Lora, Sara Sanz Rojo, Luis Collado Yurrita

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Dietary Effects on the Gut Phageome.International journal of molecular sciences · 2024
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ismael San Mauro MartínResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.ORCID 0000-0001-5873-0012
Sara López OlivaResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.
Elena Garicano VilarResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.
Guerthy Melissa Sánchez NiñoResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.
Bruno F PenadésResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.
Ana Terrén LoraResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.ORCID 0000-0002-8410-301X
Sara Sanz RojoResearch Centers in Nutrition and Health (CINUSA Group), Paseo de la Habana 43, 28036 Madrid, Spain.
Luis Collado YurritaDepartment of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0244-5065
Nutrition & Santé (Spain) · ESUniversidad Complutense de Madrid · ES

Funding

Dr. Schär NA
6 · The paper itself

Abstract

As gluten may trigger gastrointestinal disorders (GIDs), its presence or absence in the diet can change the diversity and proportion of gut microbiota. The effects of gluten after six weeks of a double-blind, placebo-controlled intervention with a gluten-free diet (GFD) were studied in participants with GIDs suffering from migraines and atopic dermatitis (n = 46). Clinical biomarkers, digestive symptoms, stool, the Migraine Disability Assessment questionnaire, and zonulin levels were analyzed. Next-generation sequencing was used to amplify the 16S rRNA gene of bacteria and the internal transcribed spacer (ITS) regions of fungi. The GFD increased Chao1 fungal diversity after the intervention, while the fungal composition showed no changes. Bacterial diversity and composition remained stable, but a positive association between bacterial and fungal Chao1 diversity and a negative association between Dothideomycetes and

Indexed as

Diet, Gluten-FreeGastrointestinal DiseasesGastrointestinal MicrobiomeGlutensMigraine DisordersAdultBacteriaDermatitis, AtopicDouble-Blind MethodFecesFemaleFungiHaptoglobinsHumansMaleMiddle AgedGlutensHaptoglobinsProtein PrecursorsRNA, Ribosomal, 16Szonulinbacteriafungigastrointestinal disordersglutenmicrobiotaMIDASzonulin

Identifiers

PMID38674918
PMCPMC11053402
OpenAlexW4395004387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.