Evidence map›Paper›PMID 38674850›Full record

ArticleNutrients2024

In Vitro Fermentation Shows Polyphenol and Fiber Blends Have an Additive Beneficial Effect on Gut Microbiota States.

Jordan A Whitman, Laurel A Doherty, Ida G Pantoja-Feliciano de Goodfellow, Kenneth Racicot, Danielle J Anderson, Katherine Kensil, J Philip Karl, Glenn R Gibson, Jason W Soares

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 21 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Current research in food science · 2025
    Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jordan A WhitmanSoldier Performance Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.
Laurel A DohertySoldier Performance Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.
Ida G Pantoja-Feliciano de GoodfellowSoldier Performance Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.
Kenneth RacicotSoldier Performance Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.
Danielle J AndersonCombat Feeding Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.
Katherine KensilCombat Feeding Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.
J Philip KarlMilitary Nutrition Division, U.S. Army Research Institute of Environmental Medicine (USARIEM), Natick, MA 01760, USA.
Glenn R GibsonFood and Nutritional Sciences, University of Reading, Reading RG6 6AH, UK.
Jason W SoaresSoldier Performance Division, U.S. Army Combat Capabilities Development Command (DEVCOM) Soldier Center, Natick, MA 01760, USA.ORCID 0009-0006-1130-3420
Combat Capabilities Development Command Soldier Center · USUniversity of Reading · GBU.S. Army Research Institute of Environmental Medicine · US

Funding

Defense Health Agency N/A
6 · The paper itself

Abstract

Polyphenols and fermentable fibers have shown favorable effects on gut microbiota composition and metabolic function. However, few studies have investigated whether combining multiple fermentable fibers or polyphenols may have additive beneficial effects on gut microbial states. Here, an in vitro fermentation model, seeded with human stool combined from 30 healthy volunteers, was supplemented with blends of polyphenols (PP), dietary fibers (FB), or their combination (PPFB) to determine influence on gut bacteria growth dynamics and select metabolite changes. PP and FB blends independently led to significant increases in the absolute abundance of select beneficial taxa, namely

Indexed as

Dietary FiberFatty Acids, VolatileFecesFermentationGastrointestinal MicrobiomeIndolesPolyphenolsAdultAmmoniaAntioxidantsBacteriaBifidobacteriumFemaleHumansLactobacillusMaleAmmoniaAntioxidantsDietary FiberFatty Acids, VolatileindoleIndolesPolyphenolsbacteriacarbohydrateextractsgut microbiomemetabolitesprebioticssupplementation

Identifiers

PMID38674850
PMCPMC11053737
OpenAlexW4394819034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.