Evidence map›Paper›PMID 38674777›Full record

ReviewMicroorganisms2024

Perspectives of FTIR as Promising Tool for Pathogen Diagnosis, Sanitary and Welfare Monitoring in Animal Experimentation Models: A Review Based on Pertinent Literature.

Matheus Morais Neves, Renan Faria Guerra, Isabela Lemos de Lima, Thomas Santos Arrais, Marco Guevara-Vega, Flávia Batista Ferreira, Rafael Borges Rosa, Mylla Spirandelli Vieira, Belchiolina Beatriz Fonseca, Robinson Sabino da Silva and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Matheus Morais NevesBiotechnology in Experimental Models Laboratory-LABME, Federal University of Uberlândia, Uberlândia 38405-330, MG, Brazil.
Renan Faria GuerraBiotechnology in Experimental Models Laboratory-LABME, Federal University of Uberlândia, Uberlândia 38405-330, MG, Brazil.
Isabela Lemos de LimaBiotechnology in Experimental Models Laboratory-LABME, Federal University of Uberlândia, Uberlândia 38405-330, MG, Brazil.ORCID 0000-0003-0953-487X
Thomas Santos ArraisBiotechnology in Experimental Models Laboratory-LABME, Federal University of Uberlândia, Uberlândia 38405-330, MG, Brazil.
Marco Guevara-VegaInnovation Center in Salivary Diagnostic and Nanotheranostics, Department of Physiology, Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlândia 38408-100, MG, Brazil.ORCID 0000-0003-2332-0886
Flávia Batista FerreiraBiotechnology in Experimental Models Laboratory-LABME, Federal University of Uberlândia, Uberlândia 38405-330, MG, Brazil.
Rafael Borges RosaRodents Animal Facilities Complex, Federal University of Uberlandia, Uberlândia 38400-902, MG, Brazil.ORCID 0000-0003-0681-6433
Mylla Spirandelli VieiraFaculty of Medicine, Maria Ranulfa Institute, Av. Vasconselos Costa 321, Uberlândia 38400-448, MG, Brazil.ORCID 0000-0003-3729-0585
Belchiolina Beatriz FonsecaSchool of Veterinary Medicine, Federal University of Uberlandia, Uberlândia 30402-018, MG, Brazil.ORCID 0000-0001-8485-078X
Robinson Sabino da SilvaInnovation Center in Salivary Diagnostic and Nanotheranostics, Department of Physiology, Institute of Biomedical Sciences, Federal University of Uberlandia, Uberlândia 38408-100, MG, Brazil.ORCID 0000-0002-2104-5780
Murilo Vieira da SilvaBiotechnology in Experimental Models Laboratory-LABME, Federal University of Uberlândia, Uberlândia 38405-330, MG, Brazil.
Universidade Federal de Uberlândia · BR

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais RED-00103-22
6 · The paper itself

Abstract

Currently, there is a wide application in the literature of the use of the Fourier Transform Infrared Spectroscopy (FTIR) technique. This basic tool has also proven to be efficient for detecting molecules associated with hosts and pathogens in infections, as well as other molecules present in humans and animals' biological samples. However, there is a crisis in science data reproducibility. This crisis can also be observed in data from experimental animal models (EAMs). When it comes to rodents, a major challenge is to carry out sanitary monitoring, which is currently expensive and requires a large volume of biological samples, generating ethical, legal, and psychological conflicts for professionals and researchers. We carried out a survey of data from the relevant literature on the use of this technique in different diagnostic protocols and combined the data with the aim of presenting the technique as a promising tool for use in EAM. Since FTIR can detect molecules associated with different diseases and has advantages such as the low volume of samples required, low cost, sustainability, and provides diagnostic tests with high specificity and sensitivity, we believe that the technique is highly promising for the sanitary and stress and the detection of molecules of interest of infectious or non-infectious origin.

Indexed as

animal facilityFourier transform infrared (FTIR)microorganisms diagnosticsanitary controlwelfare monitoring

Identifiers

PMID38674777
PMCPMC11052489
OpenAlexW4394998214

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.