Evidence map›Paper›PMID 38674756›Full record

ArticleMicroorganisms2024

Associations of Fecal Microbiota with Ectopic Fat in African Caribbean Men.

Curtis Tilves, Noel T Mueller, Joseph M Zmuda, Allison L Kuipers, Barbara Methé, Kelvin Li, John Jeffrey Carr, James G Terry, Victor Wheeler, Sangeeta Nair and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Curtis TilvesDepartment of Epidemiology, Colorado School of Public Health, Aurora, CO 80045, USA.ORCID 0000-0003-0281-5986
Noel T MuellerDepartment of Epidemiology, Colorado School of Public Health, Aurora, CO 80045, USA.
Joseph M ZmudaDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Allison L KuipersDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Barbara MethéCenter for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Kelvin LiCenter for Medicine and the Microbiome, University of Pittsburgh, Pittsburgh, PA 15213, USA.
John Jeffrey CarrDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
James G TerryDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0001-6659-3441
Victor WheelerTobago Health Studies Office, TTMF Jerningham Court, James Park Upper Scarborough, Scarborough, Trinidad and Tobago.
Sangeeta NairDepartment of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Iva MiljkovicDepartment of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-3155-9777
University of Pittsburgh · USVanderbilt University Medical Center · USColorado School of Public Health · USUniversity of Trinidad and Tobago · TT

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Epidemiology of Bone Loss in African MenR01AR049747 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZMUDA, JOSEPH M. · 2003 to 2014
$5.9M
Epidemiology of Obesity, Diabetes, and Hypertension in African CaribbeansR01HL143793 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA · 2018 to 2021
$2.7M
Effects of Dietary Patterns and Sodium Intake on the Gut Microbiome and MetabolomeR01HL166473 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI NOEL T MUELLER · 2023 to 2026
$2.4M
Ectopic adiposity in black men with high type 2 diabetes riskR01DK097084 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MILJKOVIC, IVA · 2013 to 2016
$1.9M
Johns Hopkins HIV and Heart, Lung, Blood & Sleep Disorders Training Program (H3TP)K12HL143957 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T, KIRK, GREGORY D · 2018 to 2022
$1.8M
The Effects of Diet on the Gut Microbiome and Short Chain Fatty AcidsK01HL141589 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MUELLER, NOEL T · 2018 to 2022
$845k
NCI NIH HHS P30 CA047904NHLBI NIH HHS K01 HL141589NHLBI NIH HHS K12 HL143957NHLBI NIH HHS R01 HL143793NHLBI NIH HHS R01 HL166473NIAMS NIH HHS R01 AR049747NIAMS NIH HHS R01-AR049747NIDDK NIH HHS R01 DK097084NIDDK NIH HHS R01-DK097084
6 · The paper itself

Abstract

objectiveThe gut microbiome has been associated with visceral fat (VAT) in European and Asian populations; however, associations with VAT and with ectopic fats among African-ancestry individuals are not known. Our objective was to investigate cross-sectional associations of fecal microbiota diversity and composition with VAT and ectopic fat, as well as body mass index (BMI), among middle-aged and older African Caribbean men.

methodsWe included in our analysis

resultsLower alpha diversity was associated with higher VAT and BMI, and somewhat with higher pericardial and liver fat. VAT, BMI, and pericardial fat each explained similar levels of variance in beta diversity. Gram-negative

conclusionsFecal microbiota features associated with measures of general adiposity also extend to metabolically pernicious VAT and ectopic fat accumulation in older African-ancestry men.

Indexed as

adipositybody fat distributionmicrobiomeobesity

Identifiers

PMID38674756
PMCPMC11052294
OpenAlexW4394877788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.