ReviewMicroorganisms2024
Understanding Acanthamoeba Keratitis: An In-Depth Review of a Sight-Threatening Eye Infection.
Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Oxidative Stress and Redox Imbalance inInternational journal of molecular sciences · 2026Review
- Corynebacterium bovis Keratitis Mimicking Acanthamoeba Infection Following Ocular Trauma.Cureus · 2026Article
- A Multicenter, Real-World Experience with Polyhexamethylene Biguanide (PHMB) 0.08% Monotherapy for Treating Acanthamoeba Keratitis: A Retrospective Review of 39 Cases.Ophthalmology and therapy · 2026Article
- A sustained living coating for infectious keratitis therapy via probiotic consumption and production effects.Science advances · 2026Article
- Contact lens-associated infectious keratitis: microbiological profile, management, and hygiene behaviors in a tertiary eye hospital.International ophthalmology · 2026Article
- Wessely immune rings following Keratorefractive Lenticule extraction: A case-based review.American journal of ophthalmology case reports · 2026Article
- Acanthamoeba Keratitis: 34-Year Epidemiological Profile.Antibiotics (Basel, Switzerland) · 2026Article
- Efficacy of phosphonium amphiphilic salts against Acanthamoeba genotype T4.International journal for parasitology. Drugs and drug resistance · 2026Article
- Article
- Host Response and Pathogen Load in Acanthamoeba Keratitis: A Histopathological Analysis.Investigative ophthalmology & visual science · 2026Article
- Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis.Acta ophthalmologica · 2026Article
- Inhibitory Effect of a Novel Ophthalmic Solution onLife (Basel, Switzerland) · 2025Article
- A Revised Concept for Ocular Surface Imprinting: Easy-to-Use Device for Morphological and Biomolecular-Based Differential Diagnosis.Diagnostics (Basel, Switzerland) · 2025Article
- Silver(I)-NHC Complexes as Dual-Action Agents Against PathogenicInternational journal of molecular sciences · 2025Article
- Time-Lapse Tracking of Acanthamoeba castellanii Trophozoite Activity During Exposure to Contact Lens Disinfectants.Investigative ophthalmology & visual science · 2025Article
- The Natural History of Acanthamoeba Keratitis: A Systematic Literature Review.Ophthalmology and therapy · 2025Review
- Demographic Characteristics, Contributing Risk Factors, and Prognosis ofClinical ophthalmology (Auckland, N.Z.) · 2025Article
- The hidden dancers in water: the symbiotic mystery ofFrontiers in microbiology · 2025Review
- Efficacy of physical and chemical disinfection against clinically relevant free-living amoebae isolated from drinking water and plumbing biofilms.Frontiers in microbiology · 2025Article
- The pathogenesis, risk factors, diagnosis and treatment of Acanthamoeba keratitis.Frontiers in medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acanthamoeba keratitis (AK) is a rare but potentially sight-threatening corneal infection caused by the Acanthamoeba parasite. This microorganism is found ubiquitously in the environment, often in freshwater, soil, and other sources of moisture. Despite its low incidence, AK presents significant challenges due to delayed diagnosis and the complex nature of therapeutic management. Early recognition is crucial to prevent severe ocular complications, including corneal ulceration and vision loss. Diagnostic modalities and treatment strategies may vary greatly depending on the clinical manifestation and the available tools. With the growing reported cases of Acanthamoeba keratitis, it is essential for the ophthalmic community to thoroughly understand this condition for its effective management and improved outcomes. This review provides a comprehensive overview of AK, encompassing its epidemiology, risk factors, pathophysiology, clinical manifestations, diagnosis, and treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.