Evidence map›Paper›PMID 38674663›Full record

ArticleMicroorganisms2024

Microbial Indoles: Key Regulators of Organ Growth and Metabolic Function.

Peter Yuli Xing, Ruchi Agrawal, Anusha Jayaraman, Katherine Ann Martin, George Wei Zhang, Ee Ling Ngu, Llanto Elma Faylon, Staffan Kjelleberg, Scott A Rice, Yulan Wang and 5 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Roles of Indole and Its Derivative in ModulatingInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 5 countries.

Peter Yuli XingSingapore Centre for Environmental Life Sciences Engineering, Singapore 637551, Singapore.
Ruchi AgrawalLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
Anusha JayaramanASEAN Microbiome Nutrition Centre, National Neuroscience Institute, Singapore 308433, Singapore.ORCID 0000-0002-4599-7698
Katherine Ann MartinLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.
George Wei ZhangASEAN Microbiome Nutrition Centre, National Neuroscience Institute, Singapore 308433, Singapore.
Ee Ling NguASEAN Microbiome Nutrition Centre, National Neuroscience Institute, Singapore 308433, Singapore.
Llanto Elma FaylonSingapore Centre for Environmental Life Sciences Engineering, Singapore 637551, Singapore.
Staffan KjellebergSingapore Centre for Environmental Life Sciences Engineering, Singapore 637551, Singapore.
Scott A RiceSingapore Centre for Environmental Life Sciences Engineering, Singapore 637551, Singapore.
Yulan WangLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.ORCID 0000-0002-2831-8737
Adesola T BelloDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London SW7 2AZ, UK.
Elaine HolmesDepartment of Metabolism, Digestion and Reproduction, Imperial College London, London SW7 2AZ, UK.
Jeremy K NicholsonAustralian National Phenome Centre, Health Futures Institute, Murdoch University, Perth, WA 6150, Australia.ORCID 0000-0002-8123-8349
Luke WhileyAustralian National Phenome Centre, Health Futures Institute, Murdoch University, Perth, WA 6150, Australia.ORCID 0000-0002-9088-4799
Sven PetterssonASEAN Microbiome Nutrition Centre, National Neuroscience Institute, Singapore 308433, Singapore.
Nanyang Technological University · SGMurdoch University · AUNational Neuroscience Institute · SGNational University of Singapore · SGSingapore Centre for Environmental Life Sciences Engineering · SGUK Dementia Research Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbes supporting body growth are known but the mechanisms are less well documented. Using the microbial tryptophan metabolite indole, known to regulate prokaryotic cell division and metabolic stress conditions, we mono-colonized germ-free (GF) mice with indole-producing wild-type

Indexed as

germ-freegut microbiotahost metabolismindolesorgan function declineoxidative stress

Identifiers

PMID38674663
PMCPMC11052216
OpenAlexW4393410053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.