Evidence map›Paper›PMID 38674408›Full record

ArticleGenes2024

G-Protein Signaling Modulator 2 as a Potential Biomarker in Colorectal Cancer: Integrative Analysis Using Genetic Profiling and Pan-Cancer Studies.

Doaa Jawad Kadhim, Hanieh Azari, Saeideh Khorshid Sokhangouy, Seyed Mahdi Hassanian, Hawraa Ibrahim Alshekarchi, Ladan Goshayeshi, Lena Goshayeshi, Mohammad Reza Abbaszadegan, Fatemeh Khojasteh-Leylakoohi, Majid Khazaei and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Pan-cancer analysis and oncogenic implications ofJournal of cell communication and signaling · 2025
    Article
  4. [GPSM2 is highly expressed in gastric cancer to affect patient prognosis by promoting tumor cell proliferation].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 7 countries.

Doaa Jawad KadhimMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.
Hanieh AzariMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.ORCID 0000-0002-2956-6222
Saeideh Khorshid SokhangouyMedical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad 91886-17871, Iran.
Seyed Mahdi HassanianMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.
Hawraa Ibrahim AlshekarchiAl-Zahraa Center for Medical and Pharmaceutical Research Sciences (ZCMRS), Al-Zahraa University for Women, Kerbala 56001, Iraq.
Ladan GoshayeshiDepartment of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.
Lena GoshayeshiSurgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48954, Iran.
Mohammad Reza AbbaszadeganMedical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad 91886-17871, Iran.
Fatemeh Khojasteh-LeylakoohiMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.
Majid KhazaeiMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.
Ibrahim Saeed GataaCollege of Medicine, University of Warith Al-Anbiyaa, Karbala 56001, Iraq.
Godefridus J PetersDepartment of Biochemistry, Medical University of Gdansk, 80-211 Gdansk, Poland.ORCID 0000-0002-5447-2877
Gordon A FernsDepartment of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton BN1 9PH, UK.ORCID 0000-0002-0957-8349
Jyotsna BatraFaculty of Health, School of Biomedical Sciences, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.ORCID 0000-0003-4646-6247
Alfred King-Yin LamPathology, School of Medicine and Dentistry, Gold Coast Campus, Griffith University, Gold Coast, QLD 4222, Australia.ORCID 0000-0003-2771-564X
Elisa GiovannettiCancer Center Amsterdam, Cancer Biology and Immunology, Amsterdam UMC, Vrije Universiteit, Department of Medical Oncology, 1081 HV Amsterdam, The Netherlands.ORCID 0000-0002-7565-7504
Amir AvanMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad 91779-48564, Iran.ORCID 0000-0002-4968-0962
Mashhad University of Medical Sciences · IRQueensland University of Technology · AUAl-Zahraa University for WomenAmsterdam University Medical Centers · NLBrighton and Sussex Medical School · GBFondazione Pisa · ITGriffith University · AUUniversity of Kerbala · IQ

Funding

Mashhad University of Medical Sciences 4021404
6 · The paper itself

Abstract

Colorectal cancer (CRC) imposes a significant healthcare burden globally, prompting the quest for innovative biomarkers to enhance diagnostic and therapeutic strategies. This study investigates the

Indexed as

Biomarkers, TumorColorectal NeoplasmsGene Expression Regulation, NeoplasticComputational BiologyGene Expression ProfilingHumansIntracellular Signaling Peptides and ProteinsPrognosisBiomarkers, TumorGPSM2 protein, humanIntracellular Signaling Peptides and Proteinscolorectal cancerGPSM2pan-cancerTCGA

Identifiers

PMID38674408
PMCPMC11050220
OpenAlexW4394685859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.