Evidence map›Paper›PMID 38674403›Full record

ArticleGenes2024

Genetic Modifiers of Sickle Cell Anemia Phenotype in a Cohort of Angolan Children.

Catarina Ginete, Mariana Delgadinho, Brígida Santos, Armandina Miranda, Carina Silva, Paulo Guerreiro, Emile R Chimusa, Miguel Brito

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Catarina GineteH&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.ORCID 0000-0002-2334-782X
Mariana DelgadinhoH&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.ORCID 0000-0003-0586-9154
Brígida SantosCentro de Investigação em Saúde de Angola (CISA), Bengo 9999, Angola.
Armandina MirandaInstituto Nacional de Saúde Doutor Ricardo Jorge (INSA), 1649-016 Lisbon, Portugal.
Carina SilvaH&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.ORCID 0000-0003-1021-7935
Paulo GuerreiroH&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.
Emile R ChimusaDepartment of Applied Sciences, Faculty of Health and Life Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, UK.
Miguel BritoH&TRC-Health & Technology Research Center, ESTeSL-Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, 1990-096 Lisbon, Portugal.ORCID 0000-0001-6394-658X
Instituto Politécnico de Lisboa · PTClínica Sagrada Esperança · AONational Institute of Health Dr. Ricardo Jorge · PTNorthumbria University · GBUniversity of Lisbon · PT

Funding

Aga Khan Foundation aga khanFundação para a Ciência e Tecnologia UIDB/05608/2020 and UIDP/05608/2020
6 · The paper itself

Abstract

The aim of this study was to identify genetic markers in the

Indexed as

Anemia, Sickle CellGTP-Binding ProteinsPhenotypePolymorphism, Single NucleotideAdolescentAngolaChildChild, PreschoolFemaleFetal HemoglobinGenes, ModifierHumansKruppel-Like Transcription FactorsMaleRepressor ProteinsBCL11A protein, humanerythroid Kruppel-like factorFetal HemoglobinGTP-Binding ProteinsHBS1L protein, humanKruppel-Like Transcription FactorsRepressor Proteinsnext generation sequencing (NGS)sickle cell anemia

Identifiers

PMID38674403
PMCPMC11049512
OpenAlexW4394566746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.