Evidence map›Paper›PMID 38674389›Full record

ArticleGenes2024

Relevance of

Nehal Elmansoury, Ahmed A Megahed, Ahmed Kamal, Nefertiti El-Nikhely, Marina Labane, Manal Abdelmageed, Ann K Daly, Ahmed Wahid

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Genetic Risk of MASLD in Mongolians: Role ofCurrent issues in molecular biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nehal ElmansouryDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
Ahmed A MegahedFaculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
Ahmed KamalDepartment of Internal Medicine and Hepatology, Faculty of Medicine, Alexandria University, Alexandria 21131, Egypt.ORCID 0000-0003-0957-0977
Nefertiti El-NikhelyInstitute of Graduate Studies and Research, Alexandria University, Alexandria 21526, Egypt.ORCID 0000-0002-6675-234X
Marina LabaneFaculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.ORCID 0009-0001-4108-4090
Manal AbdelmageedDepartment of Experimental and Clinical Internal Medicine, Medical Research Institute, Alexandria University, Alexandria 21561, Egypt.
Ann K DalyTranslational and Clinical Research Institute, Faculty of Medical Sciences, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
Ahmed WahidDepartment of Pharmaceutical Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria 21521, Egypt.
Alexandria University · EGNewcastle University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a frequent clinical condition globally. Single nucleotide polymorphisms (SNPs) associated with NAFLD have been proposed in the literature and based on bioinformatic screening. The association between NAFLD and genetic variants in Egyptians is still unclear. Hence, we sought to investigate the association of some genetic variants with NAFLD in Egyptians. Egyptians have been categorized into either the MASLD group (n = 205) or the healthy control group (n = 187). The severity of hepatic steatosis and liver fibrosis was assessed by a Fibroscan device. TaqMan-based genotyping assays were employed to explore the association of selected SNPs with MASLD.

Indexed as

17-Hydroxysteroid DehydrogenasesAcyltransferasesAdaptor Proteins, Signal TransducingLipaseMembrane ProteinsNon-alcoholic Fatty Liver DiseasePhospholipases A2, Calcium-IndependentPolymorphism, Single NucleotideAdultCase-Control StudiesEgyptFemaleGenetic Predisposition to DiseaseGenotypeHumansLiver Cirrhosis17-Hydroxysteroid DehydrogenasesAcyltransferasesAdaptor Proteins, Signal TransducingGCKR protein, humanHSD17B13 protein, humanLipaseMembrane ProteinsPhospholipases A2, Calcium-IndependentPNPLA3 protein, humanTM6SF2 protein, humanGCKR rs1260326 T>CHSD17B13 rs9992651 G>Anon-alcoholic fatty liver diseasePNPLA3 rs738409 C>GTM6SF2 rs58542926 C>T

Identifiers

PMID38674389
PMCPMC11049340
OpenAlexW4393945196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.