Evidence map›Paper›PMID 38674374›Full record

ArticleGenes2024

Molecular Mechanisms Associated with the Development of the Metritis Complex in Dairy Cattle.

Leanna Sanchez, Fernando Campos-Chillon, Mehdi Sargolzaei, Daniel G Peterson, Kim A Sprayberry, Garry McArthur, Paul Anderson, Bruce Golden, Siroj Pokharel, Mohammed K Abo-Ismail

Open access · goldAbstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. The Puerperium in the Modern Dairy Cow: A Review.Reproduction in domestic animals = Zuchthygiene · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Leanna SanchezDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Fernando Campos-ChillonDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Mehdi SargolzaeiSelect Sires Inc., 11740 US-42, Plain City, OH 43064, USA.
Daniel G PetersonDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Kim A SprayberryDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Garry McArthurSwinging Udders Veterinary Services, 8418 Liberty Rd, Galt, CA 95632, USA.
Paul AndersonDepartment of Computer Science and Software Engineering, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Bruce GoldenTheta Solutions LLC, Olympia, WA, USA.
Siroj PokharelDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Mohammed K Abo-IsmailDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
California Polytechnic State University · USGalderma (France) · FRUniversity of Guelph · CAWashington Department of Natural Resources · US

Funding

Agruicultural Research Institute 58855Agruicultural Research Institute 58991
6 · The paper itself

Abstract

The metritis complex (MC), a group of post-partum uterine diseases, is associated with increased treatment costs and reduced milk yield and fertility. The goal of this study was to identify genetic variants, genes, or genomic regions that modulate MC disease. A genome-wide association study was performed using a single-locus mixed linear model of 1967 genotypes (624,460 SNPs) and metritis complex records. Then, in-silico functional analyses were performed to detect biological mechanisms and pathways associated with the development of MC. The

Indexed as

Cattle DiseasesGenome-Wide Association StudyPolymorphism, Single NucleotideAnimalsCattleEndometritisFemaleGenetic Predisposition to DiseaseUterine Diseasesdairy cattlegenome-wide association studymetritis complex

Identifiers

PMID38674374
PMCPMC11049392
OpenAlexW4393357559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.