Evidence map›Paper›PMID 38674346›Full record

ArticleGenes2024

Genetic Background of Blood β-Hydroxybutyrate Acid Concentrations in Early-Lactating Holstein Dairy Cows Based on Genome-Wide Association Analyses.

Yueqiang Wang, Zhenyu Wang, Wenhui Liu, Shuoqi Xie, Xiaoli Ren, Lei Yan, Dong Liang, Tengyun Gao, Tong Fu, Zhen Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yueqiang WangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Zhenyu WangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0009-0008-8160-6560
Wenhui LiuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Shuoqi XieCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Xiaoli RenHenan Dairy Herd Improvement Center, Zhengzhou 450046, China.
Lei YanHenan Dairy Herd Improvement Center, Zhengzhou 450046, China.
Dong LiangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Tengyun GaoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Tong FuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Zhen ZhangHenan Dairy Herd Improvement Center, Zhengzhou 450046, China.
Hetian HuangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Henan Agricultural University · CNAnhui University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketosis is a common metabolic disorder in the early lactation of dairy cows. It is typically diagnosed by measuring the concentration of β-hydroxybutyrate (BHB) in the blood. This study aimed to estimate the genetic parameters of blood BHB and conducted a genome-wide association study (GWAS) based on the estimated breeding value. Phenotypic data were collected from December 2019 to August 2023, comprising blood BHB concentrations in 45,617 Holstein cows during the three weeks post-calving across seven dairy farms. Genotypic data were obtained using the Neogen Geneseek Genomic Profiler (GGP) Bovine 100 K SNP Chip and GGP Bovine SNP50 v3 (Illumina Inc., San Diego, CA, USA) for genotyping. The estimated heritability and repeatability values for blood BHB levels were 0.167 and 0.175, respectively. The GWAS result detected a total of ten genome-wide significant associations with blood BHB. Significant SNPs were distributed in

Indexed as

3-Hydroxybutyric AcidGenome-Wide Association StudyLactationPolymorphism, Single NucleotideAnimalsCattleCattle DiseasesFemaleGenetic BackgroundGenotypeKetosis3-Hydroxybutyric AcidChinese Holstein cattleestimate genetic parametersGWASketosis

Identifiers

PMID38674346
PMCPMC11049649
OpenAlexW4393181548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.