Evidence map›Paper›PMID 38674279›Full record

ReviewMedicina (Kaunas, Lithuania)2024

Endoscopic Gallbladder Drainage: A Comprehensive Review on Indications, Techniques, and Future Perspectives.

Edoardo Troncone, Rosa Amendola, Alessandro Moscardelli, Elena De Cristofaro, Pasquale De Vico, Omero Alessandro Paoluzi, Giovanni Monteleone, Manuel Perez-Miranda, Giovanna Del Vecchio Blanco

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07655778 (Multicenter Comparative Clinical Trial), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07655778 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multicenter Comparative Clinical Trial: EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON Study: (DRainage, Endoscopic Ultrasound, CONservative)

TypeinterventionalSponsorHospital Mutua de TerrassaRan2026 to 2029Enrolled110ConditionsCholecystectomy, Gallbladder, Endoscopic Ultrasound (EUS), CholelithiasisArmsEUS-guided gallbladder drainage (EUS-GBD), Conservative management (CM)
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Latest Advances in Pancreatobiliary Endoscopy.Medicina (Kaunas, Lithuania) · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Edoardo TronconeDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Rosa AmendolaDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Alessandro MoscardelliDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Elena De CristofaroDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Pasquale De VicoDepartment of Anaesthesia, University of Rome "Tor Vergata", 00133 Rome, Italy.
Omero Alessandro PaoluziDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-5393-5796
Giovanni MonteleoneDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-1339-9076
Manuel Perez-MirandaDepartment of Gastroenterology and Hepatology, University Hospital Rio Hortega, 47012 Valladolid, Spain.ORCID 0000-0003-0744-220X
Giovanna Del Vecchio BlancoDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-6327-563X
University of Rome Tor Vergata · ITHospital Universitario Río Hortega · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, therapeutic endoscopy has become a fundamental tool in the management of gallbladder diseases in light of its minimal invasiveness, high clinical efficacy, and good safety profile. Both endoscopic transpapillary gallbladder drainage (TGBD) and endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD) provide effective internal drainage in patients with acute cholecystitis unfit for cholecystectomy, avoiding the drawbacks of external percutaneous gallbladder drainage (PGBD). The availability of dedicated lumen-apposing metal stents (LAMS) for EUS-guided transluminal interventions contributed to the expansion of endoscopic therapies for acute cholecystitis, making endoscopic gallbladder drainage easier, faster, and hence more widely available. Moreover, EUS-GBD with LAMS opened the possibility of several cholecystoscopy-guided interventions, such as gallstone lithotripsy and clearance. Finally, EUS-GBD has also been proposed as a rescue drainage modality in malignant biliary obstruction after failure of standard techniques, with encouraging results. In this review, we will describe the TBGD and EUS-GBD techniques, and we will discuss the available data on clinical efficacy in different settings in comparison with PGBD. Finally, we will comment on the future perspectives of EUS-GBD, discussing the areas of uncertainty in which new data are more strongly awaited.

Indexed as

DrainageEndosonographyCholecystitis, AcuteEndoscopyGallbladderGallbladder DiseasesHumansStentsacute cholecystitisbiliary obstructioncholecystectomycholecystostomyERCPEUS-guided drainageinterventional EUStherapeutic EUS

Identifiers

PMID38674279
PMCPMC11052411
OpenAlexW4394805758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.