Evidence map›Paper›PMID 38674208›Full record

ReviewMedicina (Kaunas, Lithuania)2024

Behçet's Disease, Pathogenesis, Clinical Features, and Treatment Approaches: A Comprehensive Review.

Salvatore Lavalle, Sebastiano Caruso, Roberta Foti, Caterina Gagliano, Salvatore Cocuzza, Luigi La Via, Federica Maria Parisi, Christian Calvo-Henriquez, Antonino Maniaci

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
22.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Salvatore LavalleFaculty of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.
Sebastiano CarusoDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section, University of Catania, Via S. Sofia, 78, 95125 Catania, Italy.
Roberta FotiDivision of Rheumatology, A.O.U. "Policlinico-San Marco", 95123 Catania, Italy.ORCID 0000-0002-3074-4508
Caterina GaglianoFaculty of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.ORCID 0000-0001-8424-0068
Salvatore CocuzzaDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section, University of Catania, Via S. Sofia, 78, 95125 Catania, Italy.ORCID 0000-0002-6135-0958
Luigi La ViaDepartment of Anaesthesia and Intensive Care, University Hospital Policlinico-San Marco, 24046 Catania, Italy.ORCID 0000-0002-2156-7554
Federica Maria ParisiDepartment of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", ENT Section, University of Catania, Via S. Sofia, 78, 95125 Catania, Italy.ORCID 0009-0003-0998-726X
Christian Calvo-HenriquezService of Otolaryngology, Hospital Complex of Santiago de Compostela, 15701 Santiago de Compostela, Spain.ORCID 0000-0003-3580-0967
Antonino ManiaciFaculty of Medicine and Surgery, University of Enna "Kore", 94100 Enna, Italy.ORCID 0000-0002-1251-0185
Università degli Studi di Enna Kore · ITUniversity of Catania · ITPoliclinico Universitario di Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's disease is a systemic inflammatory disorder of unknown etiology. The disease manifests with diverse clinical symptoms, most commonly recurrent oral and genital ulcers, skin lesions, and uveitis, though it can affect multiple organ systems. Diagnosis is primarily clinical due to the lack of a definitive diagnostic test, and management involves a multidisciplinary approach to control inflammation and manage symptoms. Current treatment strategies involve corticosteroids, immunosuppressive agents, and, increasingly, biological therapies. Behçet's disease exhibits a higher prevalence along the Silk Road, suggesting a role of environmental and genetic factors. Despite significant progress in understanding its clinical characteristics and treatment approaches, gaps remain in our understanding of its pathogenesis. Future research is needed to elucidate the disease's pathophysiology and optimize treatment strategies.

Indexed as

Behcet SyndromeAdrenal Cortex HormonesHumansImmunosuppressive AgentsAdrenal Cortex HormonesImmunosuppressive AgentsBehçet’s diseaseepidemiologypathogenesis clinical featurestreatment approaches

Identifiers

PMID38674208
PMCPMC11051811
OpenAlexW4393357338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.