Evidence map›Paper›PMID 38674153›Full record

ArticleInternational journal of molecular sciences2024

The Long-Acting Serine Protease Inhibitor mPEG-SPA-MDSPI16 Alleviates LPS-Induced Acute Lung Injury.

Jingrui Chen, Xinjun Zhou, Nan Dai, Xiaoyu Liu, Shihan Liu, Haipeng Zhang, Lingcong Kong, Hongxia Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jingrui ChenCollege of Veterinary Medicine, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Xinjun ZhouCollege of Life Science, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Nan DaiCollege of Life Science, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Xiaoyu LiuCollege of Life Science, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Shihan LiuCollege of Life Science, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Haipeng ZhangCollege of Life Science, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Lingcong KongCollege of Veterinary Medicine, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Hongxia MaCollege of Veterinary Medicine, Jilin Agricultural University, Xincheng Street No. 2888, Changchun 130118, China.
Jilin Agricultural University · CN

Funding

National Natural Science Foundation U23A20242
6 · The paper itself

Abstract

Anti-inflammatory drugs have become the second-largest class of common drugs after anti-infective drugs in animal clinical care worldwide and are often combined with other drugs to treat fever and viral diseases caused by various factors. In our previous study, a novel serine protease inhibitor-encoding gene (

Indexed as

Acute Lung InjuryLipopolysaccharidesSerine Proteinase InhibitorsAnimalsAnti-Inflammatory AgentsDisease Models, AnimalHumansLeukocyte ElastaseMaleMiceNF-kappa BPolyethylene GlycolsRecombinant Fusion ProteinsSignal TransductionAnti-Inflammatory AgentsLeukocyte ElastaseLipopolysaccharidesNF-kappa BPolyethylene GlycolsRecombinant Fusion ProteinsSerine Proteinase InhibitorsALIanti-inflammatory activityanti-inflammatory mechanismmPEG-SPA-MDSPI16pharmaceutical properties

Identifiers

PMID38674153
PMCPMC11049807
OpenAlexW4395000408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.