Evidence map›Paper›PMID 38674051›Full record

ArticleInternational journal of molecular sciences2024

The SARS-CoV-2 Spike Protein Receptor-Binding Domain Expressed in Rice Callus Features a Homogeneous Mix of Complex-Type Glycans.

Guillermo Sobrino-Mengual, Victoria Armario-Nájera, Juliette Balieu, Marie-Laure Walet-Balieu, Andrea Saba-Mayoral, Ana M Pelacho, Teresa Capell, Paul Christou, Muriel Bardor, Patrice Lerouge

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Guillermo Sobrino-MengualDepartment of Agricultural and Forest Sciences and Engineering, University of Lleida, Agrotecnio CERCA Center, 25003 Lleida, Spain.ORCID 0000-0002-8992-6322
Victoria Armario-NájeraDepartment of Agricultural and Forest Sciences and Engineering, University of Lleida, Agrotecnio CERCA Center, 25003 Lleida, Spain.
Juliette BalieuGlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, IRIB, GDR CNRS Chemobiologie, RMT BESTIM, Université de Rouen Normandie, F-76000 Rouen, France.
Marie-Laure Walet-BalieuINSERM, CNRS, HeRacLeS US51 UAR2026, PISSARO, Université de Rouen Normandie, F-76000 Rouen, France.ORCID 0000-0002-1031-1916
Andrea Saba-MayoralDepartment of Agricultural and Forest Sciences and Engineering, University of Lleida, Agrotecnio CERCA Center, 25003 Lleida, Spain.
Ana M PelachoDepartment of Agricultural and Forest Sciences and Engineering, University of Lleida, Agrotecnio CERCA Center, 25003 Lleida, Spain.ORCID 0000-0002-9552-0556
Teresa CapellDepartment of Agricultural and Forest Sciences and Engineering, University of Lleida, Agrotecnio CERCA Center, 25003 Lleida, Spain.
Paul ChristouDepartment of Agricultural and Forest Sciences and Engineering, University of Lleida, Agrotecnio CERCA Center, 25003 Lleida, Spain.
Muriel BardorINSERM, CNRS, HeRacLeS US51 UAR2026, PISSARO, Université de Rouen Normandie, F-76000 Rouen, France.ORCID 0000-0002-0966-903X
Patrice LerougeGlycoMEV UR 4358, SFR Normandie Végétal FED 4277, Innovation Chimie Carnot, IRIB, GDR CNRS Chemobiologie, RMT BESTIM, Université de Rouen Normandie, F-76000 Rouen, France.
Universitat de Lleida · ESCentre National de la Recherche Scientifique · FRInstitució Catalana de Recerca i Estudis Avançats · ES

Funding

ANR agency under the ANR PRCE DAGENTA ANR-21-CE20-0038-001EU PID2022-1414160B-I00European Union's Horizon 2020 Research and Innovation Program 774078Generalitat de Catalunya 2021 SGR 01501Grand défi Biomédicament : améliorer les rendements et maîtriser les coûts de production: Nouveaux Systèmes d'Expression - 2020 PHAEOMABS project - ANR-21-F2II-0005Spanish Ministry of Science and Innovation MCIN/AEI/10.13039/501100011033/FEDERSpanish Ministry of Science, Innovation and Universities FPI fellowship PRE2019-088852
6 · The paper itself

Abstract

The spike protein receptor-binding domain (RBD) of SARS-CoV-2 is required for the infection of human cells. It is the main target that elicits neutralizing antibodies and also a major component of diagnostic kits. The large demand for this protein has led to the use of plants as a production platform. However, it is necessary to determine the

Indexed as

OryzaPolysaccharidesSARS-CoV-2Spike Glycoprotein, CoronavirusCOVID-19GlycosylationHumansPlants, Genetically ModifiedProtein BindingProtein DomainsPolysaccharidesSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2biologicsglycan profileplant molecular farmingreceptor-binding domainSARS-CoV-2spike protein

Identifiers

PMID38674051
PMCPMC11050186
OpenAlexW4394914529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.