Evidence map›Paper›PMID 38674039›Full record

ReviewInternational journal of molecular sciences2024

A Review of Antisynthetase Syndrome-Associated Interstitial Lung Disease.

Puja Patel, Jenna M Marinock, Aamir Ajmeri, Lawrence H Brent

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Myopathies in clinical care: a focus on treatable causes.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Puja PatelSection of Rheumatology, Temple University Hospital, Philadelphia, PA 19140, USA.
Jenna M MarinockDepartment of Medicine, Temple University Hospital, Philadelphia, PA 19140, USA.
Aamir AjmeriDepartment of Thoracic Medicine, Temple University Hospital, Philadelphia, PA 19140, USA.ORCID 0000-0002-7361-5300
Lawrence H BrentSection of Rheumatology, Temple University Hospital, Philadelphia, PA 19140, USA.
Temple University Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective in this review article is to present a clinical case of a patient with antisynthetase syndrome (ASyS) and provide an overview of the pathogenesis, classification criteria, antibody profiles, clinical features, and current knowledge of treatment options, focusing on interstitial lung disease (ILD). ASyS is an uncommon autoimmune disease with a heterogenous clinical presentation characterized by the presence of autoantibodies against an aminoacyl-tRNA synthetase and manifested by myositis, fever, inflammatory arthritis, Raynaud's phenomenon, mechanics hands, and ILD. ASyS-associated ILD (ASyS-ILD) is the most serious complication of ASyS, which may evolve to rapidly progressive ILD; therefore, it often requires thorough clinical and radiologic evaluation including recognition of a specific clinical phenotype associated with the antisynthetase antibodies (ASAbs) to guide therapeutic interventions.

Indexed as

AutoantibodiesLung Diseases, InterstitialMyositisAmino Acyl-tRNA SynthetasesFemaleHumansMiddle AgedAmino Acyl-tRNA SynthetasesAutoantibodiesanti-Jo-1 antibodyantisynthetase antibodiesantisynthetase syndromeidiopathic inflammatory myopathyIIMinterstitial lung disease

Identifiers

PMID38674039
PMCPMC11050089
OpenAlexW4394932815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.