Evidence map›Paper›PMID 38674030›Full record

ArticleInternational journal of molecular sciences2024

The Microglial Transcriptome of Age-Associated Deep Subcortical White Matter Lesions Suggests a Neuroprotective Response to Blood-Brain Barrier Dysfunction.

Taghreed Almansouri, Rachel Waller, Stephen B Wharton, Paul R Heath, Fiona E Matthews, Carol Brayne, Fredericus van Eeden, Julie E Simpson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Taghreed AlmansouriSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.
Rachel WallerSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.ORCID 0000-0001-5815-8829
Stephen B WhartonSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.ORCID 0000-0003-2785-333X
Paul R HeathSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.ORCID 0000-0002-8385-1438
Fiona E MatthewsInstitute for Clinical and Applied Health Research, University of Hull, Hull HU6 7RX, UK.ORCID 0000-0002-1728-2388
Carol BrayneDepartment of Psychiatry, University of Cambridge, Cambridge CB2 3EG, UK.
Fredericus van EedenSchool of Biosciences, University of Sheffield, Sheffield S10 2GF, UK.
Julie E SimpsonSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.ORCID 0000-0002-3753-4271
University of Sheffield · GBKing Abdulaziz University · SAUniversity of Cambridge · GBUniversity of Hull · GB

Funding

King Abdulaziz University PhD studentship
6 · The paper itself

Abstract

Age-associated deep-subcortical white matter lesions (DSCLs) are an independent risk factor for dementia, displaying high levels of CD68

Indexed as

AgingBlood-Brain BarrierMicrogliaTranscriptomeWhite MatterAgedAged, 80 and overAntigens, CDAntigens, Differentiation, MyelomonocyticFemaleGene Expression ProfilingHumansMaleNeuroprotectionAntigens, CDAntigens, Differentiation, Myelomonocyticdeep subcortical lesionsmicrogliatranscriptomic profiling

Identifiers

PMID38674030
PMCPMC11050386
OpenAlexW4394919558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.