Evidence map›Paper›PMID 38673958›Full record

ReviewInternational journal of molecular sciences2024

Eosinophils in Oral Disease: A Narrative Review.

Huda Moutaz Asmael Al-Azzawi, Rita Paolini, Nicola Cirillo, Lorraine Ann O'Reilly, Ilaria Mormile, Caroline Moore, Tami Yap, Antonio Celentano

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Huda Moutaz Asmael Al-AzzawiMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Rita PaoliniMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.ORCID 0000-0002-2170-4723
Nicola CirilloMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.ORCID 0000-0003-1429-1323
Lorraine Ann O'ReillyThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.ORCID 0000-0001-7134-6496
Ilaria MormileDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0001-7599-5426
Caroline MooreMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.
Tami YapMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.ORCID 0000-0001-8412-1114
Antonio CelentanoMelbourne Dental School, The University of Melbourne, 720 Swanston Street, Carlton, VIC 3053, Australia.ORCID 0000-0003-4293-2511
The University of Melbourne · AUUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of diseases characterised by eosinophilia is on the rise, emphasising the importance of understanding the role of eosinophils in these conditions. Eosinophils are a subset of granulocytes that contribute to the body's defence against bacterial, viral, and parasitic infections, but they are also implicated in haemostatic processes, including immunoregulation and allergic reactions. They contain cytoplasmic granules which can be selectively mobilised and secrete specific proteins, including chemokines, cytokines, enzymes, extracellular matrix, and growth factors. There are multiple biological and emerging functions of these specialised immune cells, including cancer surveillance, tissue remodelling and development. Several oral diseases, including oral cancer, are associated with either tissue or blood eosinophilia; however, their exact mechanism of action in the pathogenesis of these diseases remains unclear. This review presents a comprehensive synopsis of the most recent literature for both clinicians and scientists in relation to eosinophils and oral diseases and reveals a significant knowledge gap in this area of research.

Indexed as

EosinophilsMouth DiseasesAnimalsCytokinesEosinophiliaHumansCytokineseosinophilsoral canceroral diseasesoral potentially malignant disorders

Identifiers

PMID38673958
PMCPMC11050291
OpenAlexW4394854288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.