Evidence map›Paper›PMID 38673942›Full record

ArticleInternational journal of molecular sciences2024

The Inhibition Activity of Natural Methoxyflavonoid from

Jang Hoon Kim, Kyung-Sook Han, Eun-Song Lee, Yong-Goo Kim, Yong-Il Kim, Byoung Ok Cho, Ik Soo Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Journal of enzyme inhibition and medicinal chemistry · 2026
    Article
  2. Article
  3. Targeting L-arginine/NO/cGMP/KFrontiers in pharmacology · 2025
    Review
  4. Inhibitory Activity of Glycosides fromJournal of microbiology and biotechnology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jang Hoon KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Chungbuk 27709, Republic of Korea.
Kyung-Sook HanDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Chungbuk 27709, Republic of Korea.
Eun-Song LeeDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Chungbuk 27709, Republic of Korea.
Yong-Goo KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Chungbuk 27709, Republic of Korea.
Yong-Il KimDepartment of Herbal Crop Research, National Institute of Horticultural & Herbal Science, RDA, Chungbuk 27709, Republic of Korea.
Byoung Ok ChoInstitute of Health Science, Jeonju University, 303 Cheonjam-ro, Jeonju-si 55069, Republic of Korea.ORCID 0000-0001-8272-2282
Ik Soo LeeKm Covergence Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Republic of Korea.ORCID 0000-0003-4867-7646
Rural Development Administration · KRJeonju University · KRKorea Institute of Oriental Medicine · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soluble epoxide hydrolase (sEH) is an enzyme targeted for the treatment of inflammation and cardiovascular diseases. Activated inflammatory cells produce nitric oxide (NO), which induces oxidative stress and exacerbates inflammation. We identify an inhibitor able to suppress sEH and thus NO production. Five flavonoids

Indexed as

Epoxide HydrolasesFlavonoidsInulaNitric OxideAnimalsAnti-Inflammatory AgentsEnzyme InhibitorsFlowersKineticsMiceMolecular Docking SimulationRAW 264.7 CellsAnti-Inflammatory AgentsEnzyme InhibitorsEpoxide HydrolasesFlavonoidsNitric OxideflavonoidsInula britannicaNO productionsoluble epoxide hydrolase

Identifiers

PMID38673942
PMCPMC11050532
OpenAlexW4394806704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.