Evidence map›Paper›PMID 38673938›Full record

Trial reportInternational journal of molecular sciences2024

Feasibility and Preliminary Efficacy of American Elderberry Juice for Improving Cognition and Inflammation in Patients with Mild Cognitive Impairment.

Ashley F Curtis, Madison Musich, Amy N Costa, Joshua Gonzales, Hyeri Gonzales, Bradley J Ferguson, Briana Kille, Andrew L Thomas, Xing Wei, Pei Liu and 3 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. GenusInternational journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ashley F CurtisCollege of Nursing, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0002-2311-5674
Madison MusichDepartment of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0002-0811-1878
Amy N CostaCollege of Nursing, University of South Florida, Tampa, FL 33620, USA.ORCID 0000-0001-8863-3352
Joshua GonzalesSchool of Osteopathic Medicine, A. T. Still University, Kirksville, MO 63501, USA.
Hyeri GonzalesSchool of Medicine, University of Missouri, Columbia, MO 65211, USA.
Bradley J FergusonDepartment of Neurology, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0002-1636-7849
Briana KilleDepartment of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.
Andrew L ThomasDivision of Plant Science and Technology, University of Missouri, Southwest Research Extension and Education Center, Mt. Vernon, MO 65201, USA.
Xing WeiCharles W. Gehrke Proteomics Center, Department of Chemistry, University of Missouri, Columbia, MO 65201, USA.
Pei LiuCharles W. Gehrke Proteomics Center, Department of Chemistry, University of Missouri, Columbia, MO 65201, USA.
C Michael GreenliefCharles W. Gehrke Proteomics Center, Department of Chemistry, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0001-6420-7375
Joel I ShenkerDepartment of Neurology, University of Missouri, Columbia, MO 65211, USA.
David Q BeversdorfDepartment of Psychological Sciences, University of Missouri, Columbia, MO 65201, USA.ORCID 0000-0002-0298-0634
University of Missouri · USUniversity of South Florida · USChildren's Hospital Colorado · USIndiana University Indianapolis · US

Funding

Mizzou Advantage Grant N/A
6 · The paper itself

Abstract

Despite data showing that nutritional interventions high in antioxidant/anti-inflammatory properties (anthocyanin-rich foods, such as blueberries/elderberries) may decrease risk of memory loss and cognitive decline, evidence for such effects in mild cognitive impairment (MCI) is limited. This study examined preliminary effects of American elderberry (Sambucus nigra subsp. canadensis) juice on cognition and inflammatory markers in patients with MCI. In a randomized, double-blind, placebo-controlled trial, patients with MCI (

Indexed as

CognitionCognitive DysfunctionFruit and Vegetable JuicesInflammationSambucusAgedAged, 80 and overBiomarkersDouble-Blind MethodFeasibility StudiesFemaleHumansMaleSambucus nigraBiomarkerscognitionelderberryinflammatorymild cognitive impairmentproteomicssambucus

Identifiers

PMID38673938
PMCPMC11050618
OpenAlexW4394811930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.