Evidence map›Paper›PMID 38673923›Full record

ReviewInternational journal of molecular sciences2024

Dental Stem Cells and Lipopolysaccharides: A Concise Review.

Beatriz A Rodas-Junco, Sandra E Hernández-Solís, Angelica A Serralta-Interian, Florencio Rueda-Gordillo

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Drug delivery for age-related bone diseases: From therapeutic targets to common and emerging therapeutic strategies.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Beatriz A Rodas-JuncoCONAHCYT-Facultad de Ingeniería Química, Campus de Ciencias Exactas e Ingenierías, Universidad Autónoma de Yucatán, Periférico Norte Kilómetro 33.5, Tablaje Catastral 13615 Chuburná de Hidalgo Inn, Mérida CP 97203, Yucatán, Mexico.
Sandra E Hernández-SolísDepartamento de Microbiología Oral y Biología Molecular, Facultad de Odontología, Universidad Autónoma de Yucatán, Calle 61-A #492-A X Av. Itzaes Costado Sur "Parque de la Paz", Col. Centro, Mérida CP 97000, Yucatán, Mexico.ORCID 0000-0002-9276-7510
Angelica A Serralta-InterianLaboratorio Traslacional de Células Troncales de la Cavidad Bucal, Facultad de Odontología, Universidad Autónoma de Yucatán, Calle 61-A #492-A X Av. Itzaes Costado Sur "Parque de la Paz", Col. Centro, Mérida CP 97000, Yucatán, Mexico.
Florencio Rueda-GordilloDepartamento de Microbiología Oral y Biología Molecular, Facultad de Odontología, Universidad Autónoma de Yucatán, Calle 61-A #492-A X Av. Itzaes Costado Sur "Parque de la Paz", Col. Centro, Mérida CP 97000, Yucatán, Mexico.ORCID 0000-0002-3885-6555
Autonomous University of Yucatán · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dental tissue stem cells (DTSCs) are well known for their multipotent capacity and regenerative potential. They also play an important role in the immune response of inflammatory processes derived from caries lesions, periodontitis, and gingivitis. These oral diseases are triggered by toxins known as lipopolysaccharides (LPS) produced by gram-negative bacteria. LPS present molecular patterns associated with pathogens and are recognized by Toll-like receptors (TLRs) in dental stem cells. In this review, we describe the effect of LPS on the biological behavior of DTSCs. We also focus on the molecular sensors, signaling pathways, and emerging players participating in the interaction of DTSCs with lipopolysaccharides. Although the scientific advances generated provide an understanding of the immunomodulatory potential of DTSCs, there are still new reflections to explore with regard to their clinical application in the treatment of oral inflammatory diseases.

Indexed as

Dental PulpLipopolysaccharidesStem CellsAnimalsBacterial InfectionsHumansSignal TransductionToll-Like ReceptorsLipopolysaccharidesToll-Like Receptorsdental stem cellslipopolysaccharidesperiodontal diseasepulp inflammation

Identifiers

PMID38673923
PMCPMC11049850
OpenAlexW4394807871

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.