Evidence map›Paper›PMID 38673902›Full record

ArticleInternational journal of molecular sciences2024

Lectin-like Transcript-1 (LLT1) Expression in Oral Squamous Cell Carcinomas: Prognostic Significance and Relationship with the Tumor Immune Microenvironment.

Juan C de Vicente, Paloma Lequerica-Fernández, Juan P Rodrigo, Tania Rodríguez-Santamarta, Verónica Blanco-Lorenzo, Llara Prieto-Fernández, Daniela Corte-Torres, Aitana Vallina, Francisco Domínguez-Iglesias, Saúl Álvarez-Teijeiro and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Juan C de VicenteDepartment of Oral and Maxillofacial Surgery, Hospital Universitario Central de Asturias (HUCA), Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0002-0991-9465
Paloma Lequerica-FernándezInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, Carretera de Rubín s/n, 33011 Oviedo, Spain.
Juan P RodrigoInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0003-3063-0890
Tania Rodríguez-SantamartaDepartment of Oral and Maxillofacial Surgery, Hospital Universitario Central de Asturias (HUCA), Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0002-3721-119X
Verónica Blanco-LorenzoDepartment of Pathology, Hospital Universitario Central de Asturias (HUCA), Carretera de Rubín s/n, 33011 Oviedo, Spain.
Llara Prieto-FernándezInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0003-1630-890X
Daniela Corte-TorresPrincipado de Asturias Biobank, Hospital Universitario Central de Asturias (HUCA), Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0002-1517-4498
Aitana VallinaDepartment of Pathology, Hospital Universitario Central de Asturias (HUCA), Carretera de Rubín s/n, 33011 Oviedo, Spain.
Francisco Domínguez-IglesiasDepartment of Pathology, Hospital Universitario de Cabueñes, Prados 395, 33394 Gijón, Spain.
Saúl Álvarez-TeijeiroInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0002-6845-2789
Juana M García-PedreroInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, Carretera de Rubín s/n, 33011 Oviedo, Spain.ORCID 0000-0002-5891-9488
Universidad de Oviedo · ESGobierno del Principado de Asturias · ESHospital Universitario Central de Asturias · ESHospital Universitario De Cabueñes · ES

Funding

Instituto de Salud Carlos III CIBERONC CB16/12/00390Instituto de Salud Carlos III PI19/01255, PI19/00560 and PI22/00167Principado de Asturias (Spain) FICYT and FEDER from the European Union IDI/2021/000079
6 · The paper itself

Abstract

Lectin-like transcript-1 (LLT1) expression is detected in different cancer types and is involved in immune evasion. The present study investigates the clinical relevance of tumoral and stromal LLT1 expression in oral squamous cell carcinoma (OSCC), and relationships with the immune infiltrate into the tumor immune microenvironment (TIME). Immunohistochemical analysis of LLT1 expression was performed in 124 OSCC specimens, together with PD-L1 expression and the infiltration of CD20

Indexed as

Lectins, C-TypeReceptors, Cell SurfaceSquamous Cell Carcinoma of Head and NeckTumor MicroenvironmentAdultB7-H1 AntigenBiomarkers, TumorCarcinoma, Squamous CellFemaleHumansLymphocytes, Tumor-InfiltratingMacrophagesMaleMouth NeoplasmsPrognosisB7-H1 AntigenBiomarkers, TumorCLEC2D protein, humanLectins, C-TypeReceptors, Cell Surfaceoral squamous cell carcinomaLLT1PD-L1prognosisTILs

Identifiers

PMID38673902
PMCPMC11050533
OpenAlexW4394808139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.