Evidence map›Paper›PMID 38673877›Full record

ArticleInternational journal of molecular sciences2024

Quercetin Impairs the Growth of Uveal Melanoma Cells by Interfering with Glucose Uptake and Metabolism.

Aysegül Tura, Viktoria Herfs, Tjorge Maaßen, Huaxin Zuo, Siranush Vardanyan, Michelle Prasuhn, Mahdy Ranjbar, Vinodh Kakkassery, Salvatore Grisanti

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Aysegül TuraDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Viktoria HerfsDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Tjorge MaaßenDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Huaxin ZuoDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.ORCID 0000-0003-3038-8256
Siranush VardanyanDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.ORCID 0009-0002-4586-1907
Michelle PrasuhnDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.ORCID 0000-0001-7304-2963
Mahdy RanjbarDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Vinodh KakkasseryDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.ORCID 0000-0001-6212-8964
Salvatore GrisantiDepartment of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
University of Lübeck · DE

Funding

WERNER AND KLARA KREITZ-STIFTUNG, Germany F279097
6 · The paper itself

Abstract

Monosomy 3 in uveal melanoma (UM) increases the risk of lethal metastases, mainly in the liver, which serves as the major site for the storage of excessive glucose and the metabolization of the dietary flavonoid quercetin. Although primary UMs with monosomy 3 exhibit a higher potential for basal glucose uptake, it remains unknown as to whether glycolytic capacity is altered in such tumors. Herein, we initially analyzed the expression of

Indexed as

Cell ProliferationGlucoseGlycolysisMelanomaQuercetinUveal NeoplasmsCell Line, TumorChromosomes, Human, Pair 3Gene Expression Regulation, NeoplasticHumansPentose Phosphate PathwayUveal MelanomaGlucoseQuercetinglucose uptakeglycolysisoxidative stresspentose phosphate pathwayproliferationquercetinuveal melanoma

Identifiers

PMID38673877
PMCPMC11049862
OpenAlexW4394768042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.