Evidence map›Paper›PMID 38673784›Full record

ArticleInternational journal of molecular sciences2024

Serum Clusterin Concentration and Its Glycosylation Changes as Potential New Diagnostic Markers of SARS-CoV-2 Infection and Recovery Process.

Katarzyna Sołkiewicz, Izabela Kokot, Monika Kacperczyk, Violetta Dymicka-Piekarska, Justyna Dorf, Ewa Maria Kratz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Katarzyna SołkiewiczDepartment of Laboratory Diagnostics, Division of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211a, 50-556 Wroclaw, Poland.
Izabela KokotDepartment of Laboratory Diagnostics, Division of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211a, 50-556 Wroclaw, Poland.ORCID 0000-0002-3711-8614
Monika KacperczykDepartment of Laboratory Diagnostics, Division of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211a, 50-556 Wroclaw, Poland.
Violetta Dymicka-PiekarskaDepartment of Clinical Laboratory Diagnostics, Medical University of Bialystok, Waszyngtona 15A St., 15-269 Bialystok, Poland.ORCID 0000-0003-4170-0997
Justyna DorfDepartment of Clinical Laboratory Diagnostics, Medical University of Bialystok, Waszyngtona 15A St., 15-269 Bialystok, Poland.ORCID 0000-0003-2391-3307
Ewa Maria KratzDepartment of Laboratory Diagnostics, Division of Laboratory Diagnostics, Faculty of Pharmacy, Wroclaw Medical University, Borowska Street 211a, 50-556 Wroclaw, Poland.ORCID 0000-0003-2948-4574
Wroclaw Medical University · PLMedical University of Białystok · PL

Funding

Ministry of Health of the Republic of Poland SUBZ.D270.22.047 and SUBZ.D270.23.017
6 · The paper itself

Abstract

COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. Glycoprotein clusterin (CLU) has many functions such as phagocyte recruitment, complement system inhibition, apoptosis inhibition, hormone and lipid transport, as well as in the immune response. The study aimed to assess the changes in CLU concentrations and the profile and degree of CLU glycosylation between patients with severe COVID-19, convalescents, and healthy subjects (control). The profile and degree of serum CLU N-glycosylation were analyzed using lectin-ELISA with specific lectins. CLU concentrations were significantly lower and relative reactivities of CLU glycans with SNA (

Indexed as

BiomarkersClusterinCOVID-19SARS-CoV-2FemaleGlycosylationHumansLectinsMaleBiomarkersCLU protein, humanClusterinLectinsCOVID-19lectin-ELISAserum clusterin glycosylation

Identifiers

PMID38673784
PMCPMC11049940
OpenAlexW4394693704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.