Evidence map›Paper›PMID 38673761›Full record

ArticleInternational journal of molecular sciences2024

Heteromers Formed by GPR55 and Either Cannabinoid CB

Carlota Menéndez-Pérez, Rafael Rivas-Santisteban, Eva Del Valle, Jorge Tolivia, Ana Navarro, Rafael Franco, Eva Martínez-Pinilla

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Astrocytic GPR55 receptors promote glycolysis.Journal of cannabis research · 2026
    Article
  4. Neuroprotective Role of Cannabinoid CBMolecular neurobiology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Carlota Menéndez-PérezDepartment of Morphology and Cell Biology, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0002-0154-9826
Rafael Rivas-SantistebanMolecular Neurobiology Laboratory, Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0002-2078-6819
Eva Del ValleDepartment of Morphology and Cell Biology, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0002-7959-4790
Jorge ToliviaDepartment of Morphology and Cell Biology, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-8984-8849
Ana NavarroDepartment of Morphology and Cell Biology, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0001-6206-6505
Rafael FrancoMolecular Neurobiology Laboratory, Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.ORCID 0000-0003-2549-4919
Eva Martínez-PinillaDepartment of Morphology and Cell Biology, University of Oviedo, 33006 Oviedo, Spain.ORCID 0000-0002-0572-0926
Universidad de Oviedo · ESUniversitat Autònoma de Barcelona · ESUniversitat de Barcelona · ES

Funding

Instituto de Investigación Sanitaria del Principado de Asturias (ISPA) 2022-073-INTRAMUR-MAPIE
6 · The paper itself

Abstract

Multiple sclerosis (MS) is an autoimmune, inflammatory, and neurodegenerative disease of the central nervous system for which there is no cure, making it necessary to search for new treatments. The endocannabinoid system (ECS) plays a very important neuromodulatory role in the CNS. In recent years, the formation of heteromers containing cannabinoid receptors and their up/downregulation in some neurodegenerative diseases have been demonstrated. Despite the beneficial effects shown by some phytocannabinoids in MS, the role of the ECS in its pathophysiology is unknown. The main objective of this work was to identify heteromers of cell surface proteins receptive to cannabinoids, namely GPR55, CB

Indexed as

Multiple SclerosisPrefrontal CortexReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Receptors, CannabinoidAdultFemaleHumansMaleMiddle AgedProtein MultimerizationReceptors, G-Protein-CoupledUp-RegulationGPR55 protein, humanReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Receptors, CannabinoidReceptors, G-Protein-Coupledcannabinoidsendocannabinoid systemoligomerizationPLAprefrontal cortex

Identifiers

PMID38673761
PMCPMC11050292
OpenAlexW4394684453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.