Evidence map›Paper›PMID 38673632›Full record

ReviewJournal of clinical medicine2024

Spectral Photon-Counting Computed Tomography: Technical Principles and Applications in the Assessment of Cardiovascular Diseases.

Antonella Meloni, Erica Maffei, Alberto Clemente, Carmelo De Gori, Mariaelena Occhipinti, Vicenzo Positano, Sergio Berti, Ludovico La Grutta, Luca Saba, Riccardo Cau and 6 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
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  6. Clinical application of cardiac computed tomography in cardiomyopathy.The international journal of cardiovascular imaging · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Antonella MeloniBioengineering Unit, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-2284-8585
Erica MaffeiDepartment of Radiology, Istituto di Ricovero e Cura a Carattere Scientifico SYNLAB SDN, 80131 Naples, Italy.
Alberto ClementeDepartment of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-4285-9468
Carmelo De GoriDepartment of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.
Mariaelena OcchipintiDepartment of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.
Vicenzo PositanoBioengineering Unit, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0001-6955-9572
Sergio BertiDiagnostic and Interventional Cardiology Department, Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.ORCID 0000-0002-5244-0556
Ludovico La GruttaDepartment of Radiology, University Hospital "P. Giaccone", 90127 Palermo, Italy.
Luca SabaDepartment of Radiology, University Hospital of Cagliari, 09042 Monserrato (CA), Italy.ORCID 0000-0003-2870-3771
Riccardo CauDepartment of Radiology, University Hospital of Cagliari, 09042 Monserrato (CA), Italy.ORCID 0000-0002-7910-1087
Eduardo BossoneDepartment of Cardiology, Ospedale Cardarelli, 80131 Naples, Italy.ORCID 0000-0003-2769-9950
Cesare MantiniDepartment of Radiology, "G. D'Annunzio" University, 66100 Chieti, Italy.ORCID 0000-0001-6429-8836
Carlo CavaliereDepartment of Radiology, Istituto di Ricovero e Cura a Carattere Scientifico SYNLAB SDN, 80131 Naples, Italy.ORCID 0000-0002-3297-2213
Bruna PunzoDepartment of Radiology, Istituto di Ricovero e Cura a Carattere Scientifico SYNLAB SDN, 80131 Naples, Italy.ORCID 0000-0003-0915-4682
Simona CeliBioCardioLab, Fondazione G. Monasterio CNR-Regione Toscana, 54100 Massa, Italy.ORCID 0000-0002-7832-0122
Filippo CademartiriDepartment of Radiology, Fondazione G. Monasterio CNR-Regione Toscana, 56124 Pisa, Italy.ORCID 0000-0002-0579-3279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spectral Photon-Counting Computed Tomography (SPCCT) represents a groundbreaking advancement in X-ray imaging technology. The core innovation of SPCCT lies in its photon-counting detectors, which can count the exact number of incoming x-ray photons and individually measure their energy. The first part of this review summarizes the key elements of SPCCT technology, such as energy binning, energy weighting, and material decomposition. Its energy-discriminating ability represents the key to the increase in the contrast between different tissues, the elimination of the electronic noise, and the correction of beam-hardening artifacts. Material decomposition provides valuable insights into specific elements' composition, concentration, and distribution. The capability of SPCCT to operate in three or more energy regimes allows for the differentiation of several contrast agents, facilitating quantitative assessments of elements with specific energy thresholds within the diagnostic energy range. The second part of this review provides a brief overview of the applications of SPCCT in the assessment of various cardiovascular disease processes. SPCCT can support the study of myocardial blood perfusion and enable enhanced tissue characterization and the identification of contrast agents, in a manner that was previously unattainable.

Indexed as

coronary imagingmyocardial diseasephoton-counting detectorsspectral computed tomography

Identifiers

PMID38673632
PMCPMC11051476

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.