Evidence map›Paper›PMID 38673436›Full record

ReviewJournal of clinical medicine2024

Are the Spinal Changes in the Course of Scoliogeny Primary but Secondary?

Theodoros B Grivas, Elias Vasiliadis, Christina Mazioti, Despina Papagianni, Aristea Mamzeri, Michail Chandrinos, George Vynichakis, Konstantinos Athanasopoulos, Paschalis Christodoulides, Nikola Jevtic and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Segmental relationships between thoracic asymmetry and spinal deformity in mild-to-moderate idiopathic scoliosis patients at first presentation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Theodoros B GrivasTrauma and Orthopaedic Department, Former Head, "Tzaneio" General Hospital of Piraeus, 185 36 Piraeus, Greece.ORCID 0000-0003-3018-5168
Elias Vasiliadis3rd Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, KAT Hospital, 145 61 Athens, Greece.ORCID 0000-0003-2428-5250
Christina Mazioti"Tzaneio" General Hospital of Piraeus, 185 36 Piraeus, Greece.
Despina PapagianniSchool Nurse, Special Primary School of Rafina, 190 09 Rafina, Greece.
Aristea MamzeriTOMY Attica Square, 104 45 Athens, Greece.
Michail ChandrinosOrthopedic Department, Gen. Hospital of Argolida-N.M. Argous, 212 00 Argos, Greece.
George VynichakisOrthopedic Department, Gen. Hospital of Argolida-N.M. Argous, 212 00 Argos, Greece.
Konstantinos AthanasopoulosOrthopedic Department, Peristeri Medical Group, 121 32 Peristeri, Greece.
Paschalis ChristodoulidesDepartment of Radiology, General Hospital of Paphos, Paphos 8026, Cyprus.
Nikola JevticScolio Centar, 403916 Novi Sad, Serbia.ORCID 0000-0002-7065-8401
Samra PjanicDepartment of Paediatric Rehabilitation, Institute for Physical, Rehabilitation Medicine and Orthopaedic Surgery "Dr Miroslav Zotovic", 78000 Banja Luka, Bosnia and Herzegovina.
Danka LjubojevicScolio Centar, 403916 Novi Sad, Serbia.
Olga SavvidouFirst Department of Orthopaedic Surgery, School of Medicine, National and Kapodistrian University of Athens, "ATTIKON" University General Hospital, Rimini 1, 124 62 Athens, Greece.
Angelos Kaspiris3rd Department of Orthopaedics, School of Medicine, National and Kapodistrian University of Athens, KAT Hospital, 145 61 Athens, Greece.ORCID 0000-0003-3265-5522
Jarrett GrunsteinChiropractic Center Livingston, 340 E Northfield Rd # 2E, Livingston, NJ 07039, USA.
Klinički centar Vojvodine · RSNational and Kapodistrian University of Athens · GRTzaneion General Hospital · GRAthens Medical Center · GRPaphos General Hospital · CYUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this opinion article, there is an analysis and discussion regarding the effects of growth on the spinal and rib cage deformities, the role of the rib cage in scoliogeny, the lateral spinal profile in adolescent idiopathic scoliosis (AIS), the genetics and epigenetics of AIS, and the interesting and novel field investigating the sleep impact at nighttime on AIS in relation to the sequence of the scoliogenetic changes in scoliotics. The expressed opinions are mainly based on the published peer-reviewed research of the author and his team of co-authors. Based on the analysis noted above, it can be postulated that the vertebral growth changes in the spine during initial idiopathic scoliosis (IS) development are not primary-intrinsic but secondary changes. The primary cause starting the deformity is not located within the vertebral bodies. Instead, the deformations seen in the vertebral bodies are the secondary effects of asymmetrical loads exerted upon them, due to muscular loads, growth, and gravity.

Indexed as

epigeneticsgeneticsidiopathic scoliosisrib cagesleepvertebral spine

Identifiers

PMID38673436
PMCPMC11051170
OpenAlexW4394603658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.